Real tDCS, Sham tDCS
Conditions
Keywords
tDCS
Brief summary
Decisions are part of the daily life. On the neuronal level, activity in the dorsolateral prefrontal cortex (dlPFC) is important during complex decisions (e.g., whether something is emotional for a person or not). We apply transcranial direct current stimulation (tDCS) with the aim to increase dlPFC activity and thereby modulate decisions towards emotional content.
Interventions
A neuroConn DC-Stimulator PLUS (neuroCare Group, Ilmenau, Germany) will be used.
DEVICEsham transcranial direct current stimulation
A neuroConn DC-Stimulator PLUS (neuroCare Group, Ilmenau, Germany) will be used.
Sponsors
Novartis
University of Bern
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
DOUBLE (Subject, Investigator)
Masking description
Double blind design
Intervention model description
Participants are allocated to one of 2 groups: real tDCS or sham.
Eligibility
Sex/Gender
ALL
Age
20 Years to 30 Years
Healthy volunteers
Yes
Inclusion criteria
* Written informed consent * Non-smokers * Right-handedness * Native German speakers or comparable level of fluency * Normal or corrected-to-normal vision
Exclusion criteria
* Neurological or psychiatric condition (other than diagnosed cognitive impairment) * Past head injuries * Magnetizable implants * History of seizures * Current or life-time alcohol or drug abuse * Skin diseases * tES in the 3 months preceding or during the present study * Caffeine 3 hours prior to training
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Influence of Stimulation on the Decisions | 10 minutes | Number of words which were rated as positive or negative. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Profile of Mood States (POMS; before stimulation) | 3 minutes | Changes in the subjective measure mood, assessed with questionnaire Scores for each item is recorded as 0 for not at all up to 6 for very strong. A Total Mood Disturbance (TMD) score is calculated by summing the totals for the negative subscales dejection (14 items), fatigue (7 items) and discontent (7 items) and then subtracting the total for the positive subscale zest (7 items). |
| Profile of Mood States (POMS; after stimulation) | 3 minutes | Changes in the subjective measure mood, assessed with questionnaire Scores for each item is recorded as 0 for not at all up to 6 for very strong. A Total Mood Disturbance (TMD) score is calculated by summing the totals for the negative subscales dejection (14 items), fatigue (7 items) and discontent (7 items) and then subtracting the total for the positive subscale zest (7 items). |
| Positive and Negative Affect Schedule (PANAS; before stimulation) | 2 minutes | Changes in the subjective measure mood, assessed with self-report questionnaire divided into two mood scales. One scale measures a person's positive emotion and the other scale measures the negative. Each segment has ten terms, which can be rated on a scale of 1 to 5 to indicate the extent to which the respondent agrees that this applies to him (higher values means higher agreement). |
| Positive and Negative Affect Schedule (PANAS; after stimulation) | 2 minutes | Changes in the subjective measure mood, assessed with self-report questionnaire divided into two mood scales. One scale measures a person's positive emotion and the other scale measures the negative. Each segment has ten terms, which can be rated on a scale of 1 to 5 to indicate the extent to which the respondent agrees that this applies to him (higher values means higher agreement). |
Countries
Switzerland
Outcome results
None listed