Dental Caries
Conditions
Brief summary
The aim of this pilot study is to analyze if a hydroxyapatite-containing mouth gel has an influence on the calcium content of plaque.
Detailed description
\>= 20 subjects (7-11 years) use the hydroxyapatite-containing mouth gel for 3 days (3x per day); without using any other oral care product at this time. A dentist applies the gel on all teeth. At baseline and after 3 days plaque will be collected from buccal and labial surfaces (except surfaces with tartar). A split-mouth concept will be used: Subjects in group A: Baseline plaque collection: quadrant 1 and 4 Plaque collection after 3 days: quadrant 2 and 3 Subjects in group B: Baseline plaque collection: quadrant 2 and 3 Plaque collection after 3 days: quadrant 1 and 4 (The time between last application of the gel and plaque collection will be 1 h) The plaque will be dried and afterwards the calcium content of the plaque will be quantitively analyzed by atomic absorption spectroscopy (AAS). For all subjects: Calcium contents of plaque at baseline and after 3 days application will be compared by statistical methods.
Interventions
OTHERMouth gel
Stop using the mouth gel
Sponsors
Dr. Joachim Enax
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
7 Years to 11 Years
Healthy volunteers
Yes
Inclusion criteria
* Girls and boys (7-11 years) * Visible plaque * \>= 4 teeth * Good overall health
Exclusion criteria
* Allergic to one or more ingredients of the mouth gel * Medication intake (e.g. antibiotics) * Any other reason that, in the opinion of the investigator, disqualifies the subject from participating in the study
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Calcium content of plaque | 3 days | Analysis by atomic absorption spectroscopy (AAS) |
Countries
Indonesia
Outcome results
None listed