Breast Cancer Female, Colon Cancer, Non-small Cell Lung Cancer Metastatic
Conditions
Brief summary
Adaptated Physical Activity (APA) during treatment of cancer is one of the actual global health recommendation because of the benefits observed in several parameters evaluated in many clinical studies. A best knowledge of the physical and medical characteristics of patients, including type of cancer and type of treatment, is primordial to optimize the patient care and the effectiveness of APA programs. Descriptive, explorative and prospective study of 3 different populations: One population with locally advanced or metastatic non-small cell lung cancer treated with multiple therapeutic lines. Two different populations of early cancer patients and treated with a platinum-based regimen for colon cancer and a taxane-based chemotherapy for breast cancer.
Interventions
OTHERAdaptated Physical Activity
Evaluation of the physical condition and the quality of life during the course of treatment (after 8 weeks of treatment) and at the end of the treatment's line (except for breast cancer patients)
Sponsors
Centre Paul Strauss
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Woman with breast cancer treated with adjuvant chemotherapy (taxane) or patient with colon cancer treated with adjuvant regimen (FOLFOX) or patient with locally advanced or metastatic lung cancer * Patient without contraindication to the study-specific assessments * Eastern Cooperative Oncology Group ≤ 2 * Age ≥ 18 years old * Life expectancy \> 6 months * Able to speak, read and understand French * Written informed consent obtained from the patient * Registration in a national health care system
Exclusion criteria
* Patient with psychiatric, neurologic or musculoskeletal disorders * Pregnant or breastfeeding women * Minor or protected adult
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| evolution of exercise tolerance | change from baseline exercise tolerance at 12 weeks after the end of the treatment | To describe exercise tolerance, by a six-minute walk test, in patients treated for a cancer (of lung, breast or colon) after 8 weeks of treatment. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| measurement of parameters reflecting the physical condition | change from baseline physical condition at 12 weeks after the end of the treatment | To describe objective and felt fatigue by Fonctional assessment of chronic illness therapy-fatique (41 items scale) |
| measurement of the lean body mass condition | change from baseline physical condition at 12 weeks after the end of the treatment | To describe lean body mass by impedancemeter |
| measurement of the pulmonary function | change from baseline physical condition at 12 weeks after the end of the treatment | Spirometry measures lung function, specifically the amount (volume) of air that can be inhaled and exhaled |
Countries
France
Contacts
Primary ContactValerie SARTORI
Backup ContactJoris MALLARD
Outcome results
None listed