Skip to content

Can Right Toe Perfusion Index or Pleth Variability Index Predict Spinal Anesthesia Induced Hypotension?

Can we Predict Predict Spinal Anesthesia Induced Hypotension During Caesarean Section Using Right Toe Perfusion Index or Pleth Variability Index?

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03956186
Enrollment
60
Registered
2019-05-20
Start date
2019-05-21
Completion date
2019-07-11
Last updated
2019-07-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cesarean Section Complications, Hypotension, Perfusion Index, Pleth Variability Index, Spinal Anesthesia

Brief summary

Spinal anesthesia for caesarean section is associated with a decrease in systemic vascular resistance and cardiac output and may cause hypotension in a significant portion of the parturients. Hypotension during delivery may cause maternal and fetal complications. If parturients who are likely to develop hypotension after spinal anesthesia can be identified before surgery, anesthesiologists would have opportunity to take measures such as prophylactic vasopressor administration. Perfusion index (PI) measured by pulse oximetry reflects vasomotor tone which affects the degree of hypotension after spinal anesthesia. This is a non-invasive method of assessing the relative vascular tone with the use of pulse oximeter which calculates the ratio of pulsatile versus the non-pulsatile component of the blood flow. A lower PI indicates greater peripheral vasomotor tone. Pleth variability index (PVI) is calculated using maximum and minimum values of perfusion index during respiratory cycles. PVI is one of the dynamic indices that can predict fluid responsiveness. There are several studies investigating the predictive value of finger PI and PVI on hypotension after spinal anesthesia. However the aortocaval compression by the gravid uterus directly effects the lower extremity perfusion. So, in this study we aimed to investigate whether the right toe PI and PVI values at supine and left lateral positions can predict hypotension during caesarean section.

Interventions

None listed

Sponsors

Kahramanmaras Sutcu Imam University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 45 Years
Healthy volunteers
No

Inclusion criteria

* singleton parturient * planned for elective LSCS under spinal anesthesia

Exclusion criteria

* gestational age \< 36 weeks * emergency cases * placenta previa, pre-eclampsia * BMI\>40 * Reynauld disease * patient refusal * cardiovascular disease

Design outcomes

Primary

MeasureTime frameDescription
pleth variability index (PVI)perioperativePVI values (%)at supine and lateral positions, before and after spinal anesthesia will be recorded and compared between the 2 groups.
Perfusion index (PI)perioperativePI values(%)at supine and lateral positions, before and after spinal anesthesia will be recorded and compared between the 2 groups.

Secondary

MeasureTime frameDescription
blood pressure (mmHg)perioperativeblood pressure will be recorded

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026