General Anesthesia
Conditions
Brief summary
Oral carbohydrate loading until 2 h before surgery is well known to be effective in facilitating postoperative recovery and reducing complications, by maintaining homeostasis. However, there are still concerns in implementing this as a universal fasting guideline, because of the risk of pulmonary aspiration. Therefore, we designed this study to compare the two preoperative fasting guideline: (1) keep fasted from midnight until surgery, and (2) oral carbohydrate beverage 800 mL from midnight until 2 h before surgery.
Interventions
DIETARY_SUPPLEMENTpreoperative oral carbohydrate loading
Carbohydrate beverage (12.8% carbohydrates, 50 kcal/100 mL, 290 mOsm/kg) 800 mL is given to the NO-NPO group until 2 hours before surgery
Sponsors
Eunah Cho, MD
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
DOUBLE (Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* adult aged from 18 to 70 * American Society of Anesthesiologists (ASA) class I or II * absence of pregnancy * not on lactation at the time of surgery
Exclusion criteria
* delayed gastric emptying (GERD, gastrointestinal disease, diabetes) * contraindicated to NSAID or opioid * mental disorders * alcoholism * drug abuse
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Cross-sectional area of gastric antrum | 1 hour before surgery | Cross-sectional area of gastric antrum assessed by ultrasonography |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Hunger score | 1 hour before surgery | Hunger score is scored from 0 (never) to 10 (very much). |
| Thirst score | 1 hour before surgery | Thirst score is scored from 0 (never) to 10 (very much). |
| Preoperative anxiety | 1 hour before surgery | Preoperative anxiety is scored from 0 (never) to 10 (very much). |
Countries
South Korea
Outcome results
None listed