OSTAP Versus TAP for Postoperative Pain Management in Laparoscopic Cholecystectomy Patients

The Comparison of Analgesic Sparing Effects of Oblique Subcostal Transversus Abdominis Plane Block (OSTAP) and Transversus Abdominis Plane Block (TAP) in Patients Undergoing Laparoscopic Cholecystectomy

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03954795

Acronym

OSTAP/TAP

Enrollment

Registered

2019-05-17

Start date

2014-09-30

Completion date

2016-08-31

Last updated

2019-05-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain Postoperative

Keywords

TAP OSTAP Postoperative pain

Brief summary

The aim of the study is to compare the effectiveness and opioid sparing effects of TAP and OSTAP in patients undergoing laparoscopic cholecystectomy.

Detailed description

Patients undergoing laparoscopic cholecystectomy were separated into 3 groups. Group 1: Received TAP block Group 2: Received OSTAP Group 3: No Block Standard General Anesthesia was induced and maintained in all patients. At the end of the operation patient controlled analgesia with morphine was applied to all patients. Pain scores were evaluated at 0,2,4,6,12,24 hours postoperatively. Total morphine consumption and pain scores were compared.

Interventions

PROCEDURETAP

Classic TAP block performed through the petit triangle (the anterior axillary line and iliac crest)

PROCEDUREOSTAP

Modified TAP (OSTAP) block performed from the medial of linea semilunaris applying local anesthetic to the area between xiphoid and anterior iliac crest.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

OTHER

Masking

TRIPLE (Subject, Caregiver, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Inclusion criteria

* Scheduled for laparoscopic cholecystectomy * ASA status I-II

Exclusion criteria

* Local anesthetic allergy * Coagulopathy * Infection at procedure site

Design outcomes

Primary

Measure	Time frame	Description
Change in postoperative pain scores throughout time evaluated by VAS	Pain scores will be recorded for 24 hours postoperatively. The first measure will be taken immediately after surgery (time 0) and then at 2. 4. 6. 12. 24. hours.	Pain scores are going to be evaluated via VAS score. The VAS score will be scored between 0-10. 0 points is defined as no pain and 10 points is the most severe pain imaginable by the patient. A higher VAS score reflects a poor pain control.
Change in opioid Sparing effect measured through morphine amount delivered by a patient controlled analgesia device.	The amount of Morphine demanded by the patient will be recorded for 24 hours postoperatively. The first measure will be taken immediately after surgery (time 0) and then at 2. 4. 6. 12. 24. hours.	The amount of morphine demand of the patient measured through morphine delivery by the patient controlled analgesia device
Amount of total intraoperative remifentanil infusion	At the end of surgery.	The total amount of infused remifentanil throughout the surgery will be recorded from the infusion device.

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026