Ketosis, Exercise Performance, Ketoses, Metabolic
Conditions
Keywords
Ketones, Supplementation, Exercise Performance
Brief summary
The purpose of this study is to observe the effects of exogenous ketone supplements during shorter bouts of exercise testing on twenty collegiate endurance trained athletes (18-25 years of age).
Detailed description
Some believe very high fat diets (\>70% energy) can enhance exercise performance by providing additional fuel (ketones) for energy metabolism, at least for very prolonged exercise (\>3-4h). Regardless, this diet is difficult to maintain so it has been suggested that ingesting ketone salts along with a normal carbohydrate (CHO) diet might be more practical. The purpose of this study is to observe the effects of ketone salt ingestion on shorter term (up to \ 15 min) exercise performance. Endurance trained (≥2 year training experience; ≥7 h/week) collegiate athletes (n=20) of similar body mass (♀; 55-60kg; ♂; 75-80kg) and age 18-25y) consuming 5-6g CHO•kg-1•d-1) will be tested before and after 1 and 7d of ketone salt (Prüvit, Carrollton TX, US) supplementation (0.6-0.8g•kg-1•d-1). Participants will perform two exercise performance tests (a 10km cycle time trial and a 30s Wingate cycle test on separate days) before and after supplementation. Blood samples (glucose, lactic acid, and ketone concentration) will be taken at: baseline and following each performance test. It is hypothesized that ketone salt supplementation will increase blood ketone concentration but will not enhance these exercise performance tests.
Interventions
BEHAVIORAL10 km time trial
10 km Cycling time trial test will be conducted to examine the effects of the Exogenous Ketone Salts on time
BEHAVIORAL30s Wingate
30s all-out test to measure peak power output
DIETARY_SUPPLEMENTKetone
Supplement containing exogenous ketone salts
BEHAVIORALBaseline 10 km time trial
A baseline 10 km Cycling time trial test will be conducted
BEHAVIORALBaseline 30s Wingate
A baseline 30s all-out test to measure peak power output
Sponsors
Western University, Canada
Study design
Allocation
RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
OTHER
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 25 Years
Healthy volunteers
Yes
Inclusion criteria
* Healthy male or female Collegiate Endurance Trained Athletes * ≥2 year training experience; ≥7 h/week * Ages 18-25
Exclusion criteria
* Smoker * Injury that will affect exercise performance * Sedentary Behaviour * Currently following a High Fat diet/Ketogenic diet * Taking Beta Blockers or Hypertension Medication * Has Respiratory, Cardiovascular and/or Neuromuscular disease that is not cleared for exercise by a physician.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| 10 km Time trial | 15-20 Minutes | 10km time trial where participants will be measured on time to completion |
| 30s Wingate | 30 seconds | 30s Wingate all out test where participants will be measured on their peak power output |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Blood Ketones | 1-2 hours | Blood Ketones will be measured using a ketone meter |
| Blood Glucose | 1-2 hours | Blood Glucose will be measured using a Blood glucose meter |
| Blood Lactate | 1-2 hours | Blood Lactate will be measured using a lactate meter |
Countries
Canada
Contacts
Primary ContactSydney EL Isbell, BSc
Backup ContactManuel D Quinones, MSc
Outcome results
None listed