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Factors Influencing Risk of Progression of Chronic Kidney Disease

Factors Influencing Risk of Progression of Chronic Kidney Disease in Patients With Severe Renal Failure

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03954470
Acronym
FAIR-PROGRESS
Enrollment
1300
Registered
2019-05-17
Start date
2012-04-09
Completion date
2018-12-31
Last updated
2019-05-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Kidney Disease stage4

Brief summary

The aim of this study is to identify typical patterns of renal function evolution in patients with stage 4 chronic kidney disease, regularly followed in nephrology consultation and included in a French cohort.

Interventions

None listed

Sponsors

Centre Hospitalier Universitaire de Besancon
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Patients meeting the inclusion criteria of the ND-CRIS cohort (long-term follow-up in one of the centers participating in the research, with a GFR \<60mL/min /1.73m2) * Patients included in the ND-CRIS cohort on the date when the estimate of their GFR is strictly less than 30mL/min/1.73m2 and greater than or equal to 15mL/min/1.73m2 (MDRD equation). Patients should have at least two measurements of GFR \<30mL/min/1.73m2 to be included, at least one of them greater than or equal to 15mL/min/1.73m2. The date of the first GFR \<30mL/min/ 1.73m2 will be considered as the date of origin.

Exclusion criteria

* Patients with GFR ≥30mL / min / 1.73m2 or \<15mL / min / 1.73m2 * Patients who do not meet the inclusion criteria of ND-CRIS cohort (dialysis patients, transplant patients, unfollowed patients)

Design outcomes

Primary

MeasureTime frameDescription
Evolution of estimated Glomerular Filtration Rate (GFR) according to MDRD equation (modification of diet in renal disease) at each visitup to 3 years
Time between inclusion and occurrence of the progression eventup to 3 yearsprogression: initiation of an extra-renal purification technique or reduction of GFR of at least 5 mL / min / 1.73m2 compared to inclusion in FAIR-PROGRESS

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026