Blood Pressure in the Emergency Department

Prognostic Relevance of Elevated Blood Pressure in the Emergency Department

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03954119

Acronym

PREBPED

Enrollment

300272

Registered

2019-05-17

Start date

2009-01-01

Completion date

2016-03-31

Last updated

2019-05-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Blood Pressure, Emergencies, Hypertension

Keywords

blood pressure, emergency department, atherosclerotic cardiovascular disease, myocardial infarction, stroke, long-term prognosis

Brief summary

This is a cohort study based on a large sample (\> 600 000) of emergency department (ED) visits from two university hospital EDs. Information on incident disease after discharge from the ED will be collected through linkage to Swedish national in-patient register and cause of death register. The importance of blood pressure measured at the ED for incident atherosclerotic cardiovascular disease during long term follow up will be studied by Cox-regression analysis

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Attending the Emergency departments (ED) at Karolinska University hospital in Solna or Huddinge during the specified time period * Record of blood pressure measurement from the ED-visit

Design outcomes

Primary

Measure	Time frame	Description
Incident Atherosclerotic Cardiovascular Disease (ASCVD)	20161231	ASCVD was defined as a combination of fatal coronary heart disease (CHD ), (I210-I214, I219, I220, I221, I228, I229, I461 or I469), non-fatal MI (I210-I214, I219, I220, I221, I228 or I229), fatal and non-fatal ischemic stroke (I630-I635, I638 or I639). According to the International Classification of Diseases 10th edition (ICD-10).

Secondary

Measure	Time frame	Description
Incident Myocardial infarction (MI)	2016-12-31	Fatal and non-fatal Myocardial infarction (MI) I210-I214, I219, I220, I221, I228 or I229. I200 were included if combined with intervention procedure codes FNA-FNG, FNW) , according to the International Classification of Diseases 10th edition (ICD-10).
Incident All-cause stroke	2016-12-31	Fatal and non-fatal all-cause stroke. I61, I630-I635, I638, I639, I64, according to the International Classification of Diseases 10th edition (ICD-10).
Incident Heart failure	2016-12-31	I50 according to the International Classification of Diseases 10th edition (ICD-10).
Incident chronic kidney disease (CKD)	2016-12-31	I120, I131 E10.2-E10.5,E10.7,E11.2-E11.5, E11.7,E12.2-E12.5,E12.7, E13.2- E13.5,E13.7,E14.2-E14.5, E14.7 N032-037, N052-057, N18, N19, N250, Z49,Z49.0,Z49.1, Z49.2,Z49.01, Z49.02,Z49.3,Z49.31,Z49.32, Z99.2, I77.0 Z94.0 according to the International Classification of Diseases 10th edition (ICD-10).

Outcome results