Skip to content

The Effects of Three Different Modalities of Exercise in Patients With Schizophrenia

The Effects of Three Different Modalities of Exercise Training (Aerobic, Strength, Aerobic-strength) on Psychological and Physiological Correlates in Schizophrenia: a Randomized Clinical Trial

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03953664
Acronym
E-S
Enrollment
84
Registered
2019-05-16
Start date
2020-01-14
Completion date
2021-04-01
Last updated
2021-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Schizophrenia

Brief summary

Exercise has been shown to improve health in patients with schizophrenia. However, it remains unclear which modality of exercise reports better benefits. Aim: To compare the effects of different modalities of exercise training on psychological and physiological variables in schizophrenia.

Detailed description

Exercise has been shown to improve psychological, physiological, and biological correlates in patients with schizophrenia. However, it remains unclear which modality of exercise reports better health benefits. Aim: To compare the effects of three different modalities of exercise (aerobic, strength, aerobic-strength) on psychological and physiological variables in patients with schizophrenia. Design: Randomized clinical trial

Interventions

OTHERExperimental-Exercise training

Each session lass 60 minutes, during which time 20 minutes are allocated for warming up and cooling down (stretching) and 40 minutes are allocated to strength or/and aerobic training exercises.

Sponsors

Cardenal Herrera University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No

Inclusion criteria

* Diagnosis of Schizophrenia * Age between 18-65 years

Exclusion criteria

* Patients with other mental diseases * Patients with mental disabilities * Patients who present motor or behavioral pathologies that prevent the realization of the exercise training.

Design outcomes

Primary

MeasureTime frameDescription
Positive and Negative Syndrome Scale (PANSS)16 weeksSymptoms of schizophrenia are measured according to the subscale scores and total score on the PANSS which consists of 30 items scored from 1 (Absent) to 7 (Extreme). Scores range from 30 to 210, with higher scores indicating more symptoms.

Secondary

MeasureTime frameDescription
World Health Organization Quality of Life-Short version (WHOQOL-BREF)16 weeksThe WHOQOL-BREF contains 24 questions covering 4 domains plus two questions related to overall quality of life and satisfaction with health. Highes scores represent higher quality of life.
Body Mass Index (BMI)16 weeksThe BMI is defined as the body mass divided by the square of the body height.

Countries

Spain

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026