Clinical Presentation and Outcomes in Patients at Risk of Type II Myocardial InfarctioN in the emerGency Department.

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03953651

Acronym

COMING

Enrollment

1000

Registered

2019-05-16

Start date

2019-07-10

Completion date

2020-07-09

Last updated

2020-07-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Myocardial Infarction, Myocardial Oxygenation Imbalance

Brief summary

Type 2 myocardial infarction has been reported in the Universal Definition of Myocardial Infarction for more than 10 years and most studies resulted in a high mortality rate. However, little to nothing is known for both criteria to define myocardial oxygenation imbalance threshold and the outcome of these patients presenting with myocardial oxygenation imbalance. The aim of this study is to compare the outcome at 6 months for patients admitted in the emergency department with a myocardial oxygenation imbalance, depending on whether a type 2 myocardial infarction occured or not.

Interventions

OTHERFollow-up

Onset of Major Adverse Cardiovascular Event of death from all causes will be collected at 3 and 6 months after inclusion.

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* age 18 years old or older ; * At least one condition of myocardial oxygenation imbalance : * Oxygen saturation below 90% ; * Haemoglobin level below 130 grams/Liter (g/L) for men, 120 g/L for women ; * Persistent heart rate over 110 beats per minute, for more than 20 minutes ; * Persistent systolic blood pressure below 90 millimeters of mercury (mmHg) for more than 20 minutes despite fluid resuscitation ; * Persistent systolic blood pressure over 180 mmHg for more than 20 minutes.

Exclusion criteria

* Patient admitted with type 1 myocardial infarction ; * Patient presenting a condition for Non Ischemic Myocardial Infarction (pulmonary embolism, acute stroke, acute kidney failure, etc…) * Patient who declines to participate; * Pregnant or breastfeeding women ; * Patient deprived of liberty (inmate, administrative protection)

Design outcomes

Primary

Measure	Time frame	Description
Onset of a Major Adverse Cardiovascular Event at 6 months	6 months	Onset of a Major Adverse Cardiovascular Event such as: * Cardiovascular death * Non fatal myocardial infarction * Admission for acute heart failure * Non fatal stroke

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026