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Hysteroscopic Bubble Suction Test and Tubal Peristalsis (Darwish Test) in Hydrosalpnix

Hysteroscopic Bubble Suction Test and Tubal Peristalsis (Darwish Test) in Hydrosalpnix

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03953586
Enrollment
90
Registered
2019-05-16
Start date
2019-12-10
Completion date
2020-08-20
Last updated
2020-12-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tubal Patency

Keywords

laparoscopy, hysteroscopy,, tubal patency,, bubble test,, peristalsis

Brief summary

Tubal patency testing is essential for infertility evaluation. Standard tests are hysterosalpingography and laparoscopic perchromation test. In 2016, a hysteroscopic bubble suction test was described in apparently normal tubes. However, the efficacy of bubble suction test in abnormal tubes like hydrosalpnix has not been studied.

Detailed description

Nowadays, hysteroscopy is extensively used for fertility assessment. In a previous study, it is recommended to add hysteroscopy to the routine infertility work-up to achieve a better assessment of infertility cases. In 2016, hysteroscopy as a predictor test of tubal patency and tubal peristalsis was introduced. It is concluded that hysteroscopic bubble suction test is a good initial screening test for tubal patency nearly comparable to HSG and DL. It should be attempted in every case of OH prior to referral for more invasive HSG or laparoscopic chromopertubation test. Thereafter, some authors tried the same idea of bubble suction test and were over-enthusiastic with this test and considered it superior to hysterosalpingography (HSG) in detection of tubal patency in infertile women. They wrongly described HSG as a historic tool despite being recommended as a basic infertility test by many organizations. Some authors criticized the results of these studies and underestimated their clinical implication. One of the objections were lack of differentiation between normal tubes and damaged or narrowed but still patent tubes. Aim of the work: To test whether bubble suction test and osteal peristalsis are preserved or lost in cases with hydrosalpnix. Design: A prospective double blinded randomized controlled trial.

Interventions

DIAGNOSTIC_TESTBubble suction test and tubal peristalsis

Efficacy of this test in cases of hydrosalpnix (group A) and normal tubes (group B)

Sponsors

Woman's Health University Hospital, Egypt
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
FEMALE
Age
20 Years to 40 Years
Healthy volunteers
No

Inclusion criteria

* Infertility patients scheduled for combined laparoscopy and hysteroscopy

Exclusion criteria

* No HSG

Design outcomes

Primary

MeasureTime frameDescription
percentage of positive tests in both pathologic and healthy tubes6 monthsBubble suction test+ tubal peristalsis

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026