Concussion, Brain
Conditions
Brief summary
Researchers are trying to determine if the impact of a concussion on the brain is affected by anesthesia and surgery.
Detailed description
All subjects will complete pre and post procedure assessments prior to undergoing a planned surgery/anesthetic standard of care.
Interventions
A comprehensive assessment of neuropsychometric measures to evaluate cognitive functioning.
Sponsors
Mayo Clinic
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
16 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Male or Female \>16 years of age with a recent concussion (\<10 weeks) from planned procedure under anesthesia.
Exclusion criteria
* Neurologic history including history of severe cognitive disease, disorder, or delay, attention disorder, moderate to severe TBI history, neurovascular order or trauma.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Wide Range Achievement Test Fourth Edition, WRAT-4 | Pre-anesthetic to one week Post-anesthetic | Change in WRAT-4 |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Numeric Pain Scale 0-10 | Post-operatively to hospital discharge, up to 10 days. | Difference in numeric pain scale between the concussion and non-concussion group. Patients verbally select a value that is in line with the intensity of pain they have experienced in the last 24 hours. Pain Scale is recorded 0 = no pain, 10 = the most pain imaginable. |
| Oral morphine equivalent of consumed opioids | Post-operatively to hospital discharge, up to 10 days. | Difference of post-operative opioid use between the concussion and non-concussion group |
| Length of hospital stay | Post-operatively to hospital discharge, up to 30 days. | Difference between the concussion and non-concussion group |
| Cognitive Deficits identified by NeuroPsychometric Cognitive Testing | Pre-anesthetic to one week Post-anesthetic | Difference between the concussion and non-concussion group. |
| Sport Concussion Assessment Tool - 5th edition, SCAT-5 | Pre-anesthetic to one week Post-anesthetic | The SCAT5 is a standardized tool for evaluating concussions designed for use by physicians and licensed medical professionals. Difference in SCAT5 scores between the concussion and non-concussion group. SCAT5 scores the number of symptoms (0-22) present and the severity of symptoms (0-132). |
Countries
United States
Outcome results
None listed