Quadriceps Muscle
Conditions
Brief summary
The aim of this study is to determine the influence of acute resistance exercises on anatomical and biological changes in the quadriceps muscle and tendons of the knee
Interventions
OTHERAcute resistant load exercises
Leg bench and leg press acute resistant load exercises Leg-bench and leg-press acute resistant load exercises
BEHAVIORALBackground Questionnaire
Background questionnaire will be filled out by participants
OTHERPain Questionnaire
Pain questionnaire regarding pain in the knee during previous 3 months
GENETICDNA and RNA test
DNA and RNA tests will be sent to a genetic laboratory for analysis
DIAGNOSTIC_TESTUltrasound
Ultrasound of the knee joint and the quadriceps muscle and the pica tendon
DIAGNOSTIC_TESTPercutaneous Needle Core Biopsy
Core Biopsy will be taken from the quadriceps femoris muscle
Sponsors
Hillel Yaffe Medical Center
Study design
Allocation
RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 30 Years
Healthy volunteers
Yes
Inclusion criteria
* Non-professional athletes * Pass heart/lung endurance tests * Pass ergometrics testing
Exclusion criteria
* Have been injured * Had physiotherapy for back or lower limbs in past 6 months * Orthopedic surgery in lower limbs
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Genetic Changes in Knee Muscle and Tendon | One year | Comparison of results of genetic testing both before and after interventions between the 3 groups |
| Ultrasound Changes in Knee Muscle and Tendon | One year | Comparison of results of pre- and post ultrasound changes after interventions between the 3 groups |
| Biopsy Changes in Knee Muscle and Tendon | One year | Comparison of changes in biopsies taken before and after interventions between the 3 groups |
Countries
Israel
Contacts
Primary ContactEias Kassem, MD
Outcome results
None listed