The Effect of Bronchiectasis on the Exacerbation and Mortality in COPD

The Effect of Bronchiectasis on the Exacerbation and Mortality of Chronic Obstructive Pulmonary Disease

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03950531

Enrollment

122

Registered

2019-05-15

Start date

2010-01-25

Completion date

2017-01-25

Last updated

2019-05-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bronchiectasis, Chronic Obstructive Pulmonary Disease

Keywords

Bronchiectasis, Chronic Obstructive Pulmonary Disease, Exacerbation, Computed Tomography

Brief summary

Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory disease of the airways and lungs that develops against harmful particles or gases with exacerbations. Coexistence of bronchiectasis with COPD may lead to worsening of the functional parameters as well as alteration of the microbiological pattern in exacerbations and may negatively affect the exacerbation result parameters.

Detailed description

Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory disease of the airways and lungs that develops against harmful particles or gases with exacerbations. COPD exacerbations are characterized by worsening of dyspnea, coughing and expectoration. Exacerbations requiring hospitalization are the main cause of morbidity and mortality in COPD. Bronchiectasis is the irreversible extension of the bronchi. Usually follows with chronic sputum cough, airway obstruction and recurrent infection episodes. The association of bronchiectasis and COPD has long been known and its incidence is in the range of 30-50%. Coexistence of bronchiectasis with COPD may lead to worsening of the functional parameters as well as alteration of the microbiological pattern in exacerbations and may negatively affect the exacerbation result parameters.

Interventions

OTHERNo intervention

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

40 Years to 70 Years

Healthy volunteers

Inclusion criteria

* Patients who underwent thoracic tomography in the last year according to index exacerbation date were included in the study

Exclusion criteria

* Cases that mimic COPD exacerbation (pneumonia, pulmonary thromboembolism, pulmonary congestion, pneumothorax, pleural effusion, lung malignancy, asthma, asthma-COPD overlap syndrome) and patients admitted to the intensive care unit were excluded from the study.

Design outcomes

Primary

Measure	Time frame	Description
Charlson Comorbidity Index	1 hour	Comorbidity scores

Secondary

Measure	Time frame	Description
Spirometry	1 hour	Pulmonary function measurement

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026