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Fractures of the Humeral Shaft With Primary Radial Nerve Palsy

Fractures of the Humeral Shaft With Primary Radial Nerve Palsy: Do Injury Mechanism, Fracture Type, or Treatment Influence Nerve Recovery: A Retrospective Study

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03948542
Enrollment
50
Registered
2019-05-14
Start date
2014-01-01
Completion date
2015-03-01
Last updated
2019-05-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Functional Outcome, Radial Nerve Palsy

Keywords

Intramedullary nailing, ORIF, Humeral shaft fracture

Brief summary

This study addresses the question if patients with fractures of the humeral shaft and primary radial nerve palsy gain nerve recovery. Additionally the influence of injury mechanism, fracture type, and treatment modality on nerve recovery should be evaluated.

Detailed description

Adult fractures of the humeral shaft account for approximately 3% of all fractures; most can be treated nonoperatively. Due to the anatomy of the radial nerve and the entrapment between fragments in spiral fractures of the humerus, these injuries are associated with primary radial nerve palsy in up to 18%. Therefore, the purpose of this study was to assess the influence of injury mechanism, fracture type, and type of surgical treatment on time to onset of nerve recovery and time to full nerve recovery in patients with humeral shaft fractures and concomitant primary radial nerve palsy. A retrospective analysis of prospectively collected data for all patients treated with humeral shaft fracture and primary radial nerve palsy at an academic Level-I trauma center was performed. Between 1994 and 2013 a total of 615 patients with traumatic humeral shaft fractures were treated at the department. The dataset was examined for completeness and accuracy. Patients with an incomplete dataset, those with a pathologic or periprosthetic fracture, patients with non-surgical treatment, or who were younger than 18 years of age were excluded from this series. According to these criteria, a total of 50 patients with a humeral shaft fracture and primary radial nerve underwent surgical treatment

Interventions

OTHEROutcome

Nerve Recovery * NCV * Funcional assessment

Sponsors

Medical University of Vienna
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* patients treated with humeral shaft fracture and primary radial nerve palsy between 1994 and 2013 at the Department of Trauma Surgery, Medical University of Vienna * surgical treatment * complete data sets * minimum 18 years of age

Exclusion criteria

* Patients with an incomplete dataset * those with a pathologic or periprosthetic fracture * patients with non-surgical treatment * or who were younger than 18 years of age

Design outcomes

Primary

MeasureTime frameDescription
Changes in nerve recovery; Nerve recovery after humeral shaft fracture and surgical treatment, Functional assessmentthrough study completion, from date of inclusion till first documented changes in nerve recovery, from date of admission assessed up to 36 monthsFunctional assessment was routinely performed at all follow up visits including a clinical evaluation and muscle strength (M0-M5) with a manual muscle test that was graded according to Daniels and Worthingham.

Secondary

MeasureTime frameDescription
Nerve conduction studies (NCV) were performed routinely at two weeks following onset of radial nerve palsy and after 4 months in case of delayed recovery.2 weeks, 4 monthsNerve conduction studies
Radiographic examination via X-ray in two planes3, 6 and 12 months after traumaX-ray in two planes

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026