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The Prevalence of a Low Ankle-Brachial Index in Acute Cerebral Ischemia.

The Prevalence of a Low Ankle-Brachial Index in Patients With Acute Cerebral Ischemic Event.

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03948399
Enrollment
200
Registered
2019-05-13
Start date
2018-01-01
Completion date
2020-12-31
Last updated
2019-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ischemic Stroke

Keywords

Ischemic Stroke, TIA, ABI, LEAD

Brief summary

Aim of the study is assessment the prevalence of the low ankle-brachial index (ABI) defined less than or equal 0.9 in patients with acute cerebral ischemic event (stroke or transient ischemic attack) and determinate the correlation between ABI and internal carotid artery stenosis (ICAS) in the acute cerebral ischemic patients. The low ABI is a strong marker of generalized atherosclerosis. LEAD is a strong independent predictor for stroke.

Detailed description

Aim of the study is assessment the prevalence of the low ankle-brachial index (ABI) defined less than or equal 0.9 in patients with acute cerebral ischemic event (stroke or transient ischemic attack) and determinate the correlation between ABI and internal carotid artery stenosis (ICAS) in the acute cerebral ischemic patients. The ABI is a non-invasive tool useful for the diagnosis of LEAD. The low ABI is a strong marker of generalized atherosclerosis. LEAD is a strong independent predictor for stroke. Significant ICAS is prevalent among patients having LEAD. Acute ischemic stroke due to significant ICAS has poor prognosis. Patients with LEAD may be a suitable subgroup for screening for ICAS using duplex scanning. Estimating the relationship between cerebral ischemic event and the ABI value could help better guide preventive and risk reduction strategies.

Interventions

DEVICEDuplex scanning of carotid arteries

Measurement of carotid arteries

DEVICEABI measurement

ankle brachial index (ABI) assessment

Sponsors

Jan Biziel University Hospital No 2 in Bydgoszcz
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 99 Years
Healthy volunteers
No

Inclusion criteria

* Acute ischemic stroke or transient ischemic attack of anterior circulation * Consent of patient

Exclusion criteria

* primary intracranial hemorrhage, * venous sinus thrombosis, * unconsciousness, * intubation, * inability to provide and write a consent application form.

Design outcomes

Primary

MeasureTime frameDescription
ABI7 daysPrevalence of a low ankle-brachial index (ABI) in patients with acute cerebral ischemic event

Secondary

MeasureTime frameDescription
ABI/ICAS7 daysCorrelation between ABI and internal carotid artery stenosis (ICAS) in the acute cerebral ischemic patients.

Countries

Poland

Contacts

Primary ContactPaweł Sokal, Ph.D.
pawel.sokal@cm.umk.pl600954415

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026