Esophageal Achalasia, Esophagus Disorder
Conditions
Keywords
antibiotic prophylaxis, per oral endoscopic myotomy
Brief summary
No recommendation regarding antibiotic prophylaxis and preparation modalities are available for patients with esophageal motor disorders who benefit from Per-Oral Endoscopic Myotomy (POEM). The aim of our study was to evaluate the impact of antibiotic prophylaxis on the POEM's safety. This study was a comparative and multicentric retrospective analysis of a database prospectively maintained. Patients over 18 year's old with esophageal motor disorders confirmed by prior manometry, who underwent POEM were included. The primary endpoint was the occurrence of complications, as classified by Cotton, based on whether or not antibiotic prophylaxis was administered.
Interventions
DRUGAntibiotics
Sponsors
Société Française d'Endoscopie Digestive
Study design
Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Adults patients presenting a major esophageal motor disorder confirmed by prior manometry according to the Chicago classification and treated by per-oral endoscopic myotomy after a multidisciplinary meeting decision
Exclusion criteria
* Under-age patients were excluded
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The occurence of postoperative complications, according to Cotton's classification | 7 Days | Depending on whether or not antibiotic prophylaxis was administered |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| The evaluation of the efficacy of the procedure | 1 Month | According to the Eckard score |
| The occurence of perioperative and postoperative complications | 7 Days | According to Cotton's classification |
| The C-Reactive Protein and white blood cells count sampled | 1 Day | Blood test the day after the procedure, level of CRP in mg/L |
Outcome results
None listed