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Efficacy of Serratus Anterior Plane Block Mastectomy

Efficacy of Serratus Anterior Plane Block Using Bupivacaine/Magnesium Sulphate Versus Bupivacaine/Nalbuphine for Mastectomy: a Randomized Double Blinded Comparative Study

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03944759
Enrollment
40
Registered
2019-05-10
Start date
2019-05-07
Completion date
2019-12-01
Last updated
2020-02-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Complications, Postoperative Pain

Brief summary

Breast cancer is the main common cancer among females. . Inadequate control of pain may later develop into chronic pain syndrome (paraesthesias, phantom breast pain, and intercostobrachial neuralgia) in 25-40% of the patients .

Detailed description

The aim of this study is to compare the efficacy of ultrasound-guided serratus anterior plane block with bupivacaine/ magnesium versus bupivacaine/ nalbuphine in breast cancer surgery. Patients and methods nclusion criteria: -ASA I and II female patients, age 25-60 undergoing breast cancer surgery Exclusion criteria: * Patient refusal * Contraindications for regional blocks (eg. Infection at the injection site, coagulopathy) * Allergy to the drugs used in the study * Chronic pain therapy, * BMI more than 30 kg/m2

Interventions

serratus anterior plan block

Sponsors

doaa rashwan
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
DOUBLE (Subject, Caregiver)

Eligibility

Sex/Gender
FEMALE
Age
25 Years to 60 Years
Healthy volunteers
Yes

Inclusion criteria

* ASA I and II female patients, age 25-60 undergoing breast cancer surgery

Exclusion criteria

* -Patient refusal * Contraindications for regional blocks (eg. Infection at the injection site, coagulopathy) * Allergy to the drugs used in the study * Chronic pain therapy, * BMI more than 30 kg/m2

Design outcomes

Primary

MeasureTime frameDescription
time to first analgesic requirements in minuteschange from base line for 24 hourstime to first analgesic requirements in minutes by the patient

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026