Delirium, Ischemic Stroke
Conditions
Keywords
delirium, stroke, neutrophil-to-lymphocyte ratio, NLR, mortality
Brief summary
The aim of this study was to investigate the role of Neutrophil-to-Lymphocyte Ratio (NLR) and other derived white cell markers as early markers of delirium and outcome after acute ischemic stroke (AIS).
Detailed description
Delirium is an acute brain disorder, potentially reversible, commonly occurring in patients with acute ischemic stroke. The pathomechanism of delirium is related to neuroinflammatory process and oxidative stress. Search for readily available diagnostic marker that will aid clinicians in early identification of delirium is an on-going process. The aim of this study was to investigate the role of Neutrophil-to-Lymphocyte Ratio (NLR) and other derived white cell markers as early markers of delirium and outcome after acute ischemic stroke (AIS).
Interventions
DIAGNOSTIC_TESTDelirium assessment.
Full blood count analysis.
Sponsors
Pomeranian Medical University Szczecin
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* age \>18 years) * acute ischemic stroke
Exclusion criteria
* hematology disorders * incomplete laboratory testing * no data regarding follow-up
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Early-onset-delirium. | 24 hours | Delirium within 24 hours from admission. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Mortality at 30 days. | 30 days | Mortality determined at follow-up on day 30 after acute ischemic stroke. |
| Mortality at 1 year. | 1 year | Mortality determined at follow-up at 1 year after acute ischemic stroke. |
Outcome results
None listed