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What Are the Effects of Fibrinogen Concentrate Administration on Biological Parameters

What Are the Effects of Fibrinogen Concentrate Administration on Biological Parameters

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03944382
Acronym
Fibri_retro
Enrollment
125
Registered
2019-05-09
Start date
2016-01-01
Completion date
2017-12-31
Last updated
2020-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hemorrhage

Brief summary

the fibrinogen concentrate are given since 50 years with the dose of 2g for a afibrinogenemia. But this dose has been fixed 40 years ago and from now nobody discuss this quantity. Through this retrospective study the investigators tried to explore the evolution of blood test after a prescription of fibrinogen concentrate

Detailed description

the fibrinogen concentrate are given since 50 years with the dose of 2g for a afibrinogenemia. But this dose has been fixed 40 years ago and from now nobody discuss this quantity. Through this retrospective study the investigators tried to explore the evolution of blood test after a prescription of fibrinogen concentrate.

Interventions

None listed

Sponsors

Erasme University Hospital
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* all patient who received fibrinogen concentrate

Exclusion criteria

* none

Design outcomes

Primary

MeasureTime frameDescription
Evolution of fibrinogenone dayFibrinogen was measured before and after a fibrinogen factor transfusion. It will be used to calculate the delta (after - before) and mesure the efficiency of a transfusion
Evolution of FIBTEM A5®one dayFIBTEM A5® was measured before and after a fibrinogen factor transfusion. It will be used to calculate the delta (after - before) and mesure the efficiency of a transfusion

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026