Septicemia
Conditions
Keywords
FilmArray, bacteremia, septicemia, clinical impact, molecular testing, identification, positive blood culture, optimal antimicrobial treatment
Brief summary
Molecular testing is a largely validated approach allowing rapid identification of positive blood cultures. However, due to its high cost and its limited information on susceptibility, it is considered as an add-on technique reserved for specific patient populations. In our study, we specifically evaluated molecular testing in a critical care setting and measured its impact on the therapeutic management of critically ill with positive blood cultures. Through the analysis of 110 positive blood culture episodes included in both pre- and post intervention period, we measured a drastic 14h-reduction of the time to administration of the optimal antimicrobial treatment with the use of the molecular approach.
Interventions
DIAGNOSTIC_TESTFilmArray blood culture identification panel
FilmArray blood culture identification panel is performed 24 hours on 24hours and 7 days a week on positive blood cultures to accelerate pathogens detection
Sponsors
BioMérieux
Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Inclusion criteria
* adult intensive care unit patients with positive blood cultures
Exclusion criteria
* palliative care patients
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Turn Around Time to optimal treatment of septicemia | From positivity detection of positive blood culture to administration of optimal treatment (up to 48 hours) | Time in minutes |
Countries
Belgium
Outcome results
None listed