Atelectasis, Postoperative Pulmonary
Conditions
Keywords
Absorption atelectasis, Lung sono, Oxygen concentration
Brief summary
The purpose of this study is to investigate the effect of oxygen concentration during alveolar recruitment on absorption ateletasis.
Interventions
PROCEDUREFiO2_1.0
Alveolar recruitment is performed with 100% oxygen concentration after general anesthesia induction, after position change to Trendelenburg, after position change to supine, and at the end of operation.
PROCEDUREFiO2_0.4
Alveolar recruitment is performed with 40% oxygen concentration after general anesthesia induction, after position change to Trendelenburg, after position change to supine, and at the end of operation.
Sponsors
Seoul National University Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
20 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* Patients undergoing laparoscopic obstetric or colon surgery with Trendelenburg position
Exclusion criteria
* American Society of Anesthesiologists physical status IV or more * Severe cardiovascular disease * Severe chronic obstructive pulmonary disease, emphysema * History of pneumothorax, bullae * History of lung resection surgery * Conversion to laparotomy * Refusal to participate
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Modified lung ultrasound score | Intraoperative (at the end of operation, before emergence) | The score is calculated by adding up the 12 individual quadrant scores assessed using lung ultrasound. Each quadrant score ranges from 0 (minimal atelectasis)\ 3 (severe atelectasis), so the maximum total score is 36. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Modified lung ultrasound score | Postoperative 30 minutes | The score is calculated by adding up the 12 individual quadrant scores assessed using lung ultrasound. Each quadrant score ranges from 0 (minimal atelectasis)\ 3 (severe atelectasis), so the maximum total score is 36. |
| Intraoperative desaturation | Intraoperative | Oxygen saturation by pulse oximetry \<95% |
| Intraoperative partial pressure of arterial oxygen/fraction of inspired oxygen ratio | Intraoperative (20minutes after each recruitment) | Partial pressure of arterial oxygen/fraction of inspired oxygen ratio |
| Postoperative partial pressure of arterial oxygen/fraction of inspired oxygen ratio | Postoperative 30 minutes | Partial pressure of arterial oxygen/fraction of inspired oxygen ratio |
| Postoperative pulmonary complication | Postoperative 24 hours | respiratory infection, respiratory failure, pleural effusion, atelectasis, pneumothorax, atelectasis, bronchospasm, aspiration pneumonitis |
Countries
South Korea
Outcome results
None listed