Alcohol Use Disorder
Conditions
Brief summary
Directly reinforcing abstinence from alcohol with monetary incentives is an effective treatment for alcohol dependence, but barriers in obtaining frequent, verified biochemical measures of abstinence limit the dissemination of this treatment approach. As our feasibility study demonstrates, remote breathalyzer monitoring drastically improves the practicality of delivering an alcohol contingency management intervention. In Experiment 2, we will test whether the addition of remote abstinence incentives to treatment as usual improves outpatient treatment outcomes and prevents relapse following inpatient detoxification at a regional hospital system. We will also assess whether readmission rates are reduced using a newly developed smartphone app and breathalyzer.
Interventions
BEHAVIORALContingency Management
Monetary incentives are delivered to participants contingent upon on-time breathalyzer submissions and verified abstinence from alcohol.
BEHAVIORALContingency management
Monetary incentives are delivered to participants contingent upon on-time breathalyzer submissions only with no contingency on alcohol use.
Sponsors
Mikhail N Koffarnus
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Recently completed or currently completing an alcohol detoxification program through the Carilion Clinic or University of Kentucky Healthcare system. * Meet DSM-V criteria for alcohol use disorder. * Abstinent from alcohol at the time of consent.
Exclusion criteria
* Alcohol use disorder is secondary to another substance use disorder.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Pattern of abstinence from alcohol during intervention | up to 66 weeks | Breathalyzer assessments will be collected during the treatment period. This outcome measure will consist of the percentage of days without alcohol use as detected by the breathalyzers. |
| Treatment acceptability | A total of 12 assessment sessions spanning over a 66 week period | Participant ratings of treatment acceptability on a customized Treatment Acceptability questionnaire will be collected during assessment sessions. Each question will be scored from 1 (low) to 4 (high) and will assess distinct components of the treatment. Questions will be interpreted and scored individually and not be summed together. |
| Time to relapse | A total of 12 assessment sessions spanning over a 66 week period | For this outcome, we will conduct survival analyses to compare relapse across study groups. |
Countries
United States
Outcome results
None listed