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Temporal Relationship in Recovery of Muscular Pain and Functional Variables in an Experimental Muscular Pain Model in Hamstrings

Temporal Relationship in Recovery of Muscular Pain, Functional Variables and Normal Gait Pattern in an Experimental Muscular Pain Model in Hamstrings

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03942562
Enrollment
24
Registered
2019-05-08
Start date
2018-10-15
Completion date
2019-08-31
Last updated
2020-11-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain, Muscle

Keywords

DOMS, Healthy subjects, Pressure pain thresholds, Active Knee Extension test, Maximal strength, Electromyography, Plantar pressure measurement, Gait analysis

Brief summary

Basal measurements are taken in relation to the study variables. Immediately subjects perform eccentric exercise on right hamstrings to develop delayed onset muscle soreness (DOMS). Measurements of the study variables are taken in the same conditions 48, 96 and 168 hours after the exercise to study the evolution of the variables while recovering from DOMS.

Detailed description

Basal measurements are taken in relation to the study variables. The variables are: * pressure pain thresholds * electromyography values * static and dynamic plantar pressure measurement * active knee extensibility * maximal strength of knee flexors * thermography * scales of pain perception Immediately subjects perform eccentric exercise on right hamstrings to develop DOMS (delay onset muscle soreness). Measurements of the study variables are taken in the same conditions 48, 96 and 168 hours after the exercise to study the evolution of the variables while recovering from DOMS.

Interventions

None listed

Sponsors

Universidad San Jorge
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
MALE
Age
18 Years to 45 Years
Healthy volunteers
Yes

Inclusion criteria

* not sedentary subject (IPAQ scale \> 600 MET) * healthy subjects, without pain nor injury at the moment

Exclusion criteria

* subjects with acute or chronic pain on every spot of pelvis or lower limbs at the momento or for the last 3 months; * subjects with history of severe injury in the hamstrings muscles; * presence of serious illness; * presence of pathologies in relation to chronic pain (as fibromyalgia, migraine disorders, non specific and chronic lumbar pain); * not commitment for continuity in the study program;

Design outcomes

Primary

MeasureTime frameDescription
Changes in spatio temporal parameters of gaitBaseline, 48 hours, 96 hours, 1 weekChanges in spatio temporal parameters of gait over a treadmill will be measurement using an optical measurement system consisting of a transmitting and receiving bar (OptoGait System).

Secondary

MeasureTime frameDescription
Changes in active knee extension testBaseline, 48 hours, 96 hours, 1 weekChanges in range of motion (°; degrees) will be assessed in both sides using the active knee extension (AKE) test. AKE test: subject is lying prone with hip and knee flexed at 90°. Then, maximal knee extension is performed.
Changes in knee-flexors maximal isometric muscle strengthBaseline, 48 hours, 96 hours, 1 weekChanges in knee-flexors maximal isometric strength (Newton) will be assessed by using a hand-held dynamometer.
Electromyography (EMG) measurement during the testsBaseline, 48 hours, 96 hours, 1 weekElectromyography values will be taken from hamstrings during the performance of gait analysis and dynamometry
Changes in Pressure Pain ThresholdsBaseline, 48 hours, 96 hours, 1 weekChanges in pressure pain thresholds (PPT) will be determined with pressure algometry bilaterally over the leg and shoulder. PPT is defined as the exact time point where the pressure is first being perceived at painful.
Changes in static and dynamic plantar pressure measurementBaseline, 48 hours, 96 hours, 1 weekChanges in static and dynamic plantar pressure measurement will be performed in every session by using a pressure platform.
Changes in subjective perception of pain and impairment: Two questionnaire (Modified 7-item Likert Scales)48 hours, 96 hours, 1 weekTwo questionnaires (Modified 7-item Likert Scales) are filled up by the subject to show subjective perception of pain related to movement along the recovery period. Scale of pain intensity, from 0 (no pain) to 6 (higher pain intensity). Scale of functional impairment, from 0 (no impairment) to 6 (higher impairment).
Changes in thermography on hamstrings areasBaseline, 48 hours, 96 hours, 1 weekA thermography image will be taken every day of assessment. Changes in colour pixels will be analysed to determine temperature changes.

Countries

Spain

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026