Analgesia, Nerve Block, Total Knee Arthroplasty
Conditions
Keywords
adductor canal block
Brief summary
This study compares the tow technique of continues adductor canal block for total knee replacement surgery. Half participants will receive catheterization at the entrance of the adductor canal, while the other half will receive catheterization at the middle point of the adductor canal.
Interventions
PROCEDUREultrasound-guided short-axis placement of catheter at the entrance of the adductor canal
Ultrasound probe is placed at the entrance of the adductor canal in short axis ，insertion of a PAJUNK Contiplex S catheter with the tip of the catheter located at the entrance of the canal
PROCEDUREultrasound-guided long-axis placement of catheter at the middle of the adductor canal
Ultrasound probe is placed at the middle of the adductor canal in long axis with the caphelad end of the probe aligned with the entrance of the canal. insertion of a PAJUNK Contiplex S catheter with the tip of the catheter located at the middle of the canal
Sponsors
Peking Union Medical College Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* 18-80 years * Knee-arthroscopy * Written consent * ASA I-III * BMI 19-35
Exclusion criteria
* Unable to communicate with the investigators (e.g., a language barrier or a neuropsychiatric disorder). * coagulopathy or on anticoagulant medication * Allergic reactions toward drugs used in the trial * History of substance abuse * Infection at injection site * Can not be mobilised to 5 meters of walk pre-surgery
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| cumulative sulfentanil consumption at 24 hours after surgery | 24 hours after surgery |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| The pain scores at rest determined by the numeric rating scale (NRS, 0-10) | at 0,2,4,8,24,48 hours postoperatively | 11-point numerical rating scale (NRS; 0, no pain; 10, maximum pain imaginable). |
| The pain scores on adduction of the keen determined by the numeric rating scale (NRS, 0-10) | at 0,2,4,8,24,48 hours postoperatively | 11-point numerical rating scale (NRS; 0, no pain; 10, maximum pain imaginable). |
| incidence of postoperative nausea and vomiting (PONV) | within 48 hours after surgery | — |
| the strength of quadriceps femoris | 0,2,4,8,24,48 hours postoperatively | Quadriceps strength was assessed on a 0-5 scale as per the Medical Research Council Scale quadriceps motor strength(0 = no voluntary contraction possible, 1 = muscle flicker, but no movement of limb, 2 = active movement only with gravity eliminated, 3 = movement against gravity but without resistance, 4 = movement possible against some resistance and 5 = normal motor strength against resistance) |
| complications | within 3days after surgery | Record complications including catheter dislodgment, puncture point infection, leakage,falling down,et al. |
| cumulative sulfentanil consumption at other time points after surgery | 2,4,8,48 hours postoperatively | — |
| Patient satisfaction with anesthesia | within 5th day after surgery | Patient satisfaction with anesthesia was assessed using a 5-point scale (5, very satisfied; 4, satisfied; 3, neither satisfied nor dissatisfied; 2, dissatisfied; 1, very dissatisfied) |
Countries
China
Outcome results
None listed