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Management of Septic Non-union of the Tibia Using the Induced Membrane Technique

Management of Septic Non-union of the Tibia Using the Induced Membrane Technique

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03940638
Acronym
SEPT-LEG
Enrollment
18
Registered
2019-05-07
Start date
2015-09-30
Completion date
2015-11-30
Last updated
2019-05-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Septic Tibial Non-union

Brief summary

The aim of the study was to assess clinical and radiological results with the induces membrane technique, described by A. C. Masquelet in 1986, in a series of patients with septic non-union of the tibia

Detailed description

Septic tibial non-union is a therapeutic challenge that may even lead to amputation. Treatment often necessitates several chirurgical steps. It is agreed that resection must extend to several tissues (osteitis zone ans macroscopically pathological soft tissue), with associated non-union site stabilization ans effective antibiotic therapy. In 1986, Pr A. C. Masquelet described a 2-step procedure called the induced membrane technique, to manage bone defects of varying severity. Initial results were encouraging but there have been few large homogeneous series specific to this technique in septic non-union.

Interventions

OTHERData collection

Data collection

Sponsors

CHU de Reims
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

: * Patients with septic non-union of the tibia * managed using the induced membrane technique between novembrer 2007 and novembre 2014 in Reims University hospital * Patients who agree to participate to the study * Major patient

Exclusion criteria

: * Patient under law protection * Minor patient

Design outcomes

Primary

MeasureTime frameDescription
Presence of Bone unionDay 0Bone union was defined by 2 continuous cortices on 2 views (radiologic images comprising 2 perpendicular views of the affected segment)

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026