Chronic Obstructive Pulmonary Disease
Conditions
Brief summary
To compare the effects of high flow nasal oxygen with usual care during an outpatient 6-week pulmonary rehabilitation program after hospitalization for COPD exacerbation.
Detailed description
This is a pilot randomized controlled trial to compare the effects of high flow nasal oxygen with usual care during an outpatient 6-week pulmonary rehabilitation program after hospitalization for COPD exacerbation.
Interventions
OTHERUsual care
Usual Care
High flow nasal oxygen
Sponsors
Changi General Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
21 Years to No maximum
Healthy volunteers
No
Inclusion criteria
1. Age 21 years and above 2. Known diagnosis of COPD based on history AND spirometry demonstrating post bronchodilator FEV1/FVC ratio \<0.7 3. Currently admitted inpatient for an acute COPD exacerbation as the primary diagnosis 4. Fit to participate in exercise therapy as determined by both physician and physiotherapist 5. Has the mental capacity to follow instructions 6. Experience shortness of breath on exertion 7. Have decreased ability to carry out activities due to shortness of breath 8. Willing to participate in the exercise program
Exclusion criteria
1. Uncontrolled/ unstable medical conditions such as severe chronic heart failure that make exercise unsafe 2. Pulmonary disorder other than COPD 3. Physical conditions that preclude the ability to participate in exercise or may impair exercise performance.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| 6-minute walk distance | 6 weeks | It is the maximum distance walked in 6 minutes |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| COPD Assessment Test score | 3 weeks, 6 weeks and 1 month after completion of program | Chronic obstructive pulmonary disease assessment test (CAT) score |
| Hospital Anxiety Depression Scale | 3 weeks, 6 weeks and 1 month after completion of program | This scale has 2 subscale scores of 1) Depression 2) Anxiety. Scores of 0-7 = Normal, 8-10 = Borderline, 11-21 = Abnormal |
| Respiratory function test | 3 weeks, 6 weeks and 1 month after completion of program | It is a test of respiratory function |
| 6-minute walk distance | 3 weeks and 1 month after completion of program | It is the maximum distance walked in 6 minutes |
Countries
Singapore
Contacts
Primary ContactYingjuan Mok, MBS
Backup ContactNur Shameerah Abdul Halim
Outcome results
None listed