Postpartum Hemorrhage
Conditions
Brief summary
The aim of this study is to evaluate the renal outcome of patients undergoing elective C/S where oxytocin or carbetocin is used for postpartum hemorrhage prophylaxis.
Interventions
DRUGOxytocin
To be given to Oxytocin group following the clamping of the umbilical cord
DRUGCarbetocin
To be given to Carbetocin group following the clamping of the umbilical cord
Sponsors
Ufuk University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* Term (\>37 weeks of gestation) uncomplicated pregnant women undergoing elective cesarean section
Exclusion criteria
* Patients refusing to participate in the study * Complicated pregnancies * Patients with risk factors for postpartum hemorrhage * Contraindications for oxytocin or carbetocin usage * Patients with known renal diseases * Preterm births (\<37 weeks of gestation)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Urine volume | Intraoperative period | Total amount of intraoperative urine output in milliliters |
| Urinary sodium | Preoperative, Postoperative 2nd, 4th, 24th hours | The change in urinary sodium content (milligrams) compared to the preoperative period |
| Blood sodium | Preoperative, Postoperative 2nd, 4th, 24th hours | The change in blood sodium content (milligrams) compared to the preoperative period |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Blood transfusion | Starting from the clamping of the umbilical cord, ending at the 24th postoperative hour | Total volume (milliliters) of blood transfused |
| Need for additional uterotonics | Starting from the preoperative period, ending at the 24th postoperative hour | Total dose (milligrams) of additional uterotonics administered |
| Blood osmolality | Preoperative, Postoperative 2nd, 4th, 24th hours | The change in blood osmolality compared to the preoperative period |
| Blood loss | Intraoperative period | The total volume of intraoperative blood loss |
Countries
Turkey (Türkiye)
Contacts
Primary ContactGamze S Çağlar, Prof.Dr.
Backup ContactBaturay K Kazbek, MD
Outcome results
None listed