Infrapyloric and Greater Curvature Lymph Node Metastasis in Colon Cancer

Infrapyloric (No.206) and Greater Curvature (No.204) Lymph Node Metastasis in Adenocarcinoma Located at Hepatic Flexure and Right Half of Transverse Colon

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03936530

Enrollment

432

Registered

2019-05-03

Start date

2019-10-20

Completion date

2026-08-01

Last updated

2024-03-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal Neoplasm

Keywords

colon adenocarcinoma, lymph node metastasis, right hemi-colectomy

Brief summary

The infrapyloric (No.206) and greater curvature (No.204) lymph node metastasis in adenocarcinoma located at hepatic flexure and right half of transverse colon has not been well discribed and analysed. The aim of this study is to assess the rate of this lymph node metastasis and to reveal its prognostic value for colon cancer located at hepatic flexure and right half of transverse colon. Meanwhile, we can evaluate the safety and feasibility of this extented lymphadenectomy in right hemi-colectomy.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 75 Years

Healthy volunteers

Inclusion criteria

* Age between 18 and 75 years * American Society of Anesthesiologists (ASA) score I to III * A biopsy proven histological diagnosis of colorectal carcinoma * tumor located at hepatic flexure and right half of transverse colon * Undergoing right hemi-colectomy with extented lymphadenectomy of infrapyloric (No.206) and greater curvature (No.204) lymph node * Preoperative staging cT2-4aN0M0 or cTanyN+M0 * Willing to participate and informed consent signed

Exclusion criteria

* Pregnant or lactating women * Synchronous colorectal carcinoma * History of colorectal cancer or other malignant tumors * Clinical evidence of metastasis * Preoperative staging cT1N0 or cT4bNany * Emergency procedure

Design outcomes

Primary

Measure	Time frame	Description
metastasis rate	an average of 1 year	metastasis rate of infrapyloric (No.206) and greater curvature (No.204) lymph node

Secondary

Measure	Time frame	Description
lymphadenectomy time	an average of 1 year	time of lymphadenectomy of infrapyloric (No.206) and greater curvature (No.204) lymph node
intraoperative complication	an average of 1 year	intraoperative complication
postoperative complication	an average of 1 year	postoperative complication
3-year DFS	an average of 3 years	3-year disease free survival

Countries

China

Outcome results