Cardiac Remodeling, Ventricular, STEMI, Thyroid
Conditions
Brief summary
This study aims to determine whether thyroid hormone levels are predictive of cardiac remodeling following myocardial infarction and the prognosis in patients with STEMI receiving primary percutaneous coronary intervention.
Interventions
OTHERThyroid hormone levels
This is an observational study. Exposure: Different thyroid hormone levels.
Sponsors
Beijing Friendship Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* with a confirmed STEMI diagnosis * undergoing primary percutaneous coronary intervention (presenting \<12h after symptom onset) * patients agreed and provided informed consent
Exclusion criteria
* past history of myocardial infarction or percutaneous coronary intervention or coronary artery bypass graft * past history of heart failure (LVEF\<40%) or myocardiopathy or atrial fibrillation * past history of thyroid diseases, or were treated with amiodarone, dopamine, or corticosteroids before hospital admission * contraindicating to cardiac magnetic resonance imaging
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| MACE (major adverse cardiovascular events) | 12 months | cardiovascular death, re-infarction, revascularization, and stroke |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| adverse cardiac remodeling | 6 months | a cut-off value of 12% change in left ventricular end-diastolic volume between the acute and follow-up magnetic resonance scans |
| all-cause death | 12 months | death caused by all reason |
Countries
China
Contacts
Primary ContactHongwei Li
Outcome results
None listed