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Intraocular Pressure and Optic Nerve Sheath Diameter Changes in Laparoscopic Cholecystectomies

Intraocular Pressure and Optic Nerve Sheath Diameter Changes in Laparoscopic Cholecystectomies

Status
Withdrawn
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03933254
Enrollment
0
Registered
2019-05-01
Start date
2019-05-31
Completion date
2020-01-31
Last updated
2021-12-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intracranial Pressure, Intraocular Pressure, Pneumoperitoneum

Keywords

Intraocular pressure, Optic nerve sheath diameter, Pneumoperitoneum, Laparoscopy, Laparoscopic surgery

Brief summary

Pneumoperitoneum created during laparoscopic surgeries has some effects on human physiology. Increased intraabdominal pressure results in increased intrathoracic pressure, and eventually may result in increased intracranial and intraocular pressures. In this study we aimed to identify intraocular and intracranial pressure changes during the perioperative period due to the pneumoperitoneum created for laparoscopic cholecystectomy surgeries. Intraocular pressure will be measured directly from the eye. Intracranial pressure will be estimated by measuring optic nerve sheath diameter changes ultrasonographically.

Interventions

DIAGNOSTIC_TESTIntraocular pressure measurement via ocular tonometry

Intraocular pressure and optic nerve sheath diameter changes of the patients undergoing laparoscopic cholecystectomy will be measured throughout the surgery at different times using ocular tonometry and ultrasound, respectively.

Sponsors

Marmara University
Lead SponsorOTHER

Study design

Observational model
OTHER
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No

Inclusion criteria

* Patients undergoing laparoscopic cholecystectomy * American Society of Anesthesiologists (ASA) 1 or 2 physical status patients * Elective surgeries

Exclusion criteria

* Patients with glaucoma * ASA 3 or above patients * Emergency surgeries

Design outcomes

Primary

MeasureTime frameDescription
Intraocular pressureThroughout the operation (usually about 1 hour).The normal physiological value for intraocular pressure is 10-20 mm Hg. It is affected by pneumoperitoneum created for laparoscopy. The pressure will be measured via ocular tonometry through the eye during the surgery at predetermined time intervals.

Secondary

MeasureTime frameDescription
Intracranial pressureThroughout the operation (usually about 1 hour).The normal physiological value for intracranial pressure is below 10 mm Hg. It is affected by pneumoperitoneum created for laparoscopy. The pressure will be estimated through changes in the optic nerve sheath diameter which will be measured by ultrasonography through the eye during the surgery at predetermined time intervals.

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026