Infertility
Conditions
Keywords
cognitive psychotherapy, progressive muscular relaxation, in vitro fertilization and embryo transfer(IVF-ET), Couples Therapy
Brief summary
The in vitro fertilization and embryo transfer(IVF-ET) is a therapy to help the infertile couples. The mental health status of couple under IVF-ET, commonly seen in depression and anxiety, is found to be closely related to the success of IVF-ET. This study aims to develop a intervention program combing cognitive psychotherapy and progressive muscle relaxation to ease the negative emotion and promote the success rate among couples undergoing IVF-ET.
Interventions
BEHAVIORALCognitive progressive muscular relaxation therapy
This therapy combines cognitive psychotherapy and progressive muscular relaxation, intervened 6 times with 1-1.5 hour each time. The whole therapy will last round 28-30 days during IVF-ET.
Sponsors
Central South University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* The couple who are eligible for in vitro fertilization-embryo transfer (IVF-ET) treatment; * Junior high school and above; * voluntarily accepted for investigation and signed informed consent.
Exclusion criteria
* Suffering from physical diseases such as severe heart, liver and kidney, and mental disorders; * Experiencing major traumatic events in the past 2 years.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change of depression score | The investigators will measure the socre of depression at baseline and immediately after intervention ( the duration of intervention is around 1 month). | The Self-reported Depression Scale （SDS）will be used to assess the score of depression.The total score of SDS ranges from 0-80, with 40 as the cutoff. The higher the total score, the more depressive. |
| Change of anxiety score | The investigators will measure the socre of anxiety at baseline and immediately after intervention ( the duration of intervention is around 1 month). | The Self-reported Anxiety Scale (SAS) will be used to assess the score of anxiety.The total score of SAS ranges from 0-80, with 30 as the cutoff. The higher the total score, the more anxious. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change of Blood Cortisol | The investigators will measure the socre of Blood Cortisol at baseline and immediately after intervention ( the duration of intervention is around 1 month). | This is a kind of hormone closely related to stress, and the investigators will measure the level of Blood Cortisol by Blood test. |
| Change of sleeping quality | The investigators will measure the socre of sleeping quality at baseline and immediately after intervention ( the duration of intervention is around 1 month). | The physical condition closely related to stress. The investigators will use Self-Rating Scale of Sleep to measure the sleeping quality of the participants. The total sore ranges from 5 to 50, with higher score reflects better sleep quality. |
| Successful conception rate (%) | The doctor will test whether it is successfully conceived 4 weeks after the embryo is implanted. The last intervention is on the day of embryo implantation. The investigators will count this 4 weeks after completion of intervention. | The investigators will count the successful conception rate at each arms. |
Countries
China
Outcome results
None listed