Skip to content

Association Between a Peri-traumatic Dissociation State and the Occurrence of Post-traumatic Stress Syndrome

Study of the Association Between a Peri-traumatic Dissociation State and the Occurrence of Post-traumatic Stress Syndrome After Severe Trauma Requiring General Anesthesia

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03930966
Acronym
DIStress-AG
Enrollment
148
Registered
2019-04-29
Start date
2019-04-09
Completion date
2021-12-15
Last updated
2022-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

General Anaesthesia, Severe Trauma

Keywords

Severe trauma, General anaesthesia, Peri-traumatic dissociation state, Post-traumatic stress disorder

Brief summary

Patients will be selected after studying clinical records.Patients who had general anesthesia due to an injury related to severe trauma within 6 to 12 months prior to inclusion will be included. Three self-survey will be completed by the patient: PDEQ, PCL-5 and a demographic questionnaire. According to the PDEQ and PCL-5 scores, an association between a peri-traumatic dissociation state and a post-traumatic stress disorder can be established.

Interventions

DIAGNOSTIC_TESTPDEQ, PCL-5 and demographic survey

Questionnaires

Sponsors

University Hospital, Brest
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
PREVENTION
Masking
NONE

Intervention model description

Prospective Study

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

* Patients with general anesthesia for a surgical wound with violent trauma in the road, a fall of more than 6 meters, burn, accident at work, explosion, aggression) in the 6 to 12 months before the inclusion * Time between trauma and general anesthesia should not exceed 48 hours * Patient agreeing to participate in the study.

Exclusion criteria

* Minor patients * Patients under curatorship, and tutorship * Patient deprived of liberty * Patients who do not speak French * Patients who are not in satisfactory neurological state to answer the questionnaire (pyschotic, demented states) * Patients who have been sedated (apart from general anesthesia) when receiving or having a Glasgow score \<14

Design outcomes

Primary

MeasureTime frameDescription
Studying association between the presence of peri-traumatic dissociation state and the achievement of post-traumatic stress disorder between 6 and 12 months in traumatized patientsstudy baseline (6 to 12 months after initial hospitalisation)Association will be measured using PDEQ scale and PCL-5 scale. The peri-traumatic dissociation will be evaluated by the Peri-traumatique Dissociation Experience Questionnary (PDEQ scale). This questionnaire contains ten items to study the presence or not of a peri-traumatic dissociation state. The items are scored on a 5-point Likert scale ranging from 1 (not at all true) to 5 (extremely true). The total score is the sum of all the items. A score from 15 indicates a significant dissociation. The presence or not of a Post-Traumatic Stress Disorder (PTSD) will be evaluated by the Post-Traumatic Stress Disorder Checklist Scale-Version DSM 5 (PCL-5). This questionnaire contains twenty items to study the presence or not of a PTSD. A total score for symptom severity (0-80) can be obtained by summing the scores for each of the 20 items. A score over 31 indicates a PTSD.

Secondary

MeasureTime frame
Measurement of the frequency of PTSD after severe trauma requiring general anesthesia.study baseline (6 to 12 months after initial hospitalisation)
Research of Risk Factors Associated with the Occurrence of PTSDstudy baseline (6 to 12 months after initial hospitalisation)

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026