White Spot Lesion of Tooth
Conditions
Brief summary
During re-mineralization of white spot lesion, Will biomimetic self-assembling peptides improve the re-mineralizating effect of the post orthodontic white spot lesion compared to fluoride-based delivery systems?
Detailed description
Conservative dentistry no longer prefers the drill and fill concept and advocates reversal of lesions via remineralization. . Remineralization is the process of restoring minerals - again, in the form of mineral ions - to the hydroxyapatite latticework structure. It is three-dimensional, and the lost ions must be replaced with ions having the exact same shape, size and the same electrical charge as those lost from the lattice. Fluoride and self-assembling peptides have been used as adjuncts to enhance remineralization.
Interventions
DRUGSelf Assembling peptide
enamel regeneration
DRUGremineralizing agent
enamel regeneration
Sponsors
Raneen Ahmed
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
12 Years to 22 Years
Healthy volunteers
Yes
Inclusion criteria
* Patients with post orthodontic white spot lesion. * Patients with good oral hygiene. * Patients with good general health. * Cooperative patients. * Subjects who signed the informed consent.
Exclusion criteria
* Patients with tetracycline pigmentation and dental fluorosis. * Enamel cavitation. * Disable patient. * patient with any systemic disease or severe medical complications.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Remineralizing process | 6 months | using DIAGNOpen. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Visual assessment | 6 months | using ICDAS II |
Contacts
Primary Contactraneen ahmed gohar, Assistant lecturer
Backup Contactsherine hafez ibrahim, Assistant lecturer
Outcome results
None listed