Mortality Prediction
Conditions
Keywords
Burn injury, Mortality prediction, SOFA score, Organ failure
Brief summary
SOFA score is valid for mortality predictor for critically-ill patient in high care and intensive care burn unit
Interventions
OTHERSOFA score
Variables of sequential organ failure assessment score, including: P:F ratio; MAP or vasoactive treatment; creatinine or 24-h diuresis; platelet count; serum bilirubin; GCS.
Sponsors
Indonesia University
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* adult patients (age 18 and above) who admitted to burn unit during sampling period
Exclusion criteria
* patients discharged or deceased less than 24 hours of admission * patients referred to other hospital within 30 days admission
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| SOFA score Discrimination | 30 days from admission | SOFA score ability to discriminate outcomes based on variable scores: PaO2/FiO2; MAP/vasoactive treatment; serum creatinine or 24-h diuresis; platelet count; serum bilirubin; GCS |
| SOFA score Calibration | 30 days from admission | SOFA score cutoff to predict outcome based on variable scores: PaO2/FiO2; MAP/vasoactive treatment; serum creatinine or 24-h diuresis; platelet count; serum bilirubin; GCS |
| Correlation between SOFA score variables with outcome | 30 days from admission | Correlation between patient outcomes with each SOFA score variable: PaO2/FiO2; MAP/vasoactive treatment; serum creatinine or 24-h diuresis; platelet count; serum bilirubin; GCS |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| SOFA score: Serum creatinine or 24-hour diuresis | Day 1 | The score for serum creatinine or 24-hour diuresis variable cutoff: 0 point for creatinine \<1.2 mg/dL; 1. point for creatinine 1.2 - 1.9 mg/dL; 2. points for creatinine 2.0 - 3.4 mg/dL; 3. points for creatinine 3.5 - 4.9 mg/dL OR diuresis \<500 mL/24h; 4. points for creatinine \>5.0 mg/dL OR diuresis \<200 mL/24h. |
| SOFA score: Platelet count | Day 1 | The score for platelet count variable cutoff: 0 point for \>=150 x10\^3/mm\^3; 1. point for \<150 x10\^3/mm\^3; 2. points for \<100 x10\^3/mm\^3; 3. points for \<50 x10\^3/mm\^3; 4. points for \<20 x10\^3/mm\^3. |
| Patient outcome | 30 days from admission | Patient outcome within 30 days of admission to burn units: deceased or survived |
| SOFA score: Glasgow Coma Scale (GCS) | Day 1 | The score for GCS variable cutoff: 0 point for 15; 1. point for 13 - 14; 2. points for 10 - 12; 3. points for 6 - 9; 4. points for \<6L. |
| SOFA score: Serum Bilirubin | Day 1 | The score for serum bilirubin variable cutoff: 0 point for \<1.2 mg/dL; 1. point for 1.2 - 1.9 mg/dL; 2. points for 2.0 - 5.9 mg/dL; 3. points for 6.0 - 11.9 mg/dL; 4. points for \>12.0 mg/dL. |
| SOFA score: Partial Oxygen Pressure (PaO2)/ Fraction of Inspired Oxygen (FiO2) | Day 1 | The score for PaO2/FiO2 variable cutoff: 0 point for \>400 mmHg; 1. point for \<400 mmHg; 2. points for \<300 mmHg; 3. points for \<200 mmHg with respiratory support; 4. points for \<100 mmHg with respiratory support. |
| SOFA score: Mean Arterial Pressure (MAP) or vasoactive agent usage | Day 1 | The score for MAP or vasoactive agent usage variable cutoff: 0 point for MAP \>=70 mmHg; 1. point for MAP \<70 mmHg; 2. points for dopamine \<= 5 mcg/kg/min OR dobutamine any dose; 3. points for dopamine \>5 mcg/kg/min OR norepinephrine or epinephrine \<=0.1 mcg/kg/min; 4. points for dopamine \>15 mcg/kg/min OR norepinephrine or epinephrine \>0.1 mcg/kg/min. |
Countries
Indonesia
Outcome results
None listed