Frail Elderly Syndrome, Gastrointestinal Disease
Conditions
Keywords
Gastrointestinal surgery, Frailty, Elder patient, Complication
Brief summary
Patients aged 65 or older under gastrointestinal surgery will be enrolled，the investigators will assess the frailty of these patients by Frailty Index Scale and explore the correlation between the frailty and perioperative adverse events.
Detailed description
Patients will be assessed by specially trained doctors or nurses after admission, including daily living ability, physiological function, social-psychological status, comorbidities, mental state, grip strength, walking speed. After the assessment, the patients' frailty index was obtained. Moreover, the operation time, intraoperative bleeding loss, perioperative complications, length of stay, hospitalization expenses, readmission rate within 30 days, mortality within 30 days and other outcome indicators of these patients will be recorded. The Main purposes of present study are to verify the feasibility of applying Frailty Index (FI) to assess the degree of frailty in elderly patients undergoing gastrointestinal surgery, compare the difference of perioperative adverse events in elderly patients with different degrees of frailty，find potential indicators for evaluating and predicting the safety of surgery in elderly patients, and provide reference data for the determination of future assessment tools of frailty. The secondary objective is to compare the quality of life and long-term prognosis(only for patients with cancers,including recurrence free survival and overall survival) of elderly patients with different degrees of frailty after gastrointestinal surgery.
Interventions
OTHERFrailty Index Scale
We will evaluate the frailty with a Frailty Index Scale in elderly patients undergoing gastrointestinal surgery.
Sponsors
Ziqiang Wang,MD
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
65 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients whose age not less than 65 years; * undergoing operation in gastrointestinal surgery of West China hospital due to gastrointestinal disease.
Exclusion criteria
* Those who did not undergo surgery for various reasons; * Death before operation
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Mortality within 30 days | 2 year | death rate within 30 days after surgery in all patients after operation |
| Hospital costs | 2 year | Cost of diagnosis and treatment during hospitalization |
| Readmission rate within 30 days | 2 year | The proportion of patients who are re-hospitalized for postoperative complications after 30 days of discharge in all subjects. |
| operative time | 2 year | From the beginning of the skin incision to the end of the last incision was From the beginning of the skin incision to the end of the suture of last incision |
| Blood loss | 2 year | intraoperative blood loss |
| Intraoperative complications | 2 year | Including all the complications in the procedure |
| postoperative complications | 2 year | including incision infection，anastomotic leakage，respiratory infection, postoperative bleeding and so on. |
| The length of stay in intensive care unit (ICU) | 2 year | Time form entry to ICU to return to general ward after the condition is stable. |
| The length of hospitalization | 2 year | Time from admission to discharge |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Overall survival (OS) | 2 year | OS is the abbreviation of overall survival , which refers to the duration from postoperation to death of the subjects (Only for patients with cancers). |
| Recurrence-free Survival (RFS) | 2 year | RFS is the abbreviation of recurrence-free survival, which refers to the duration from postoperation to tumor recurrence (Only for patients with cancers). |
Countries
China
Outcome results
None listed