Skip to content

Stress in Medical Staff and Controls

Stress in Medical Staff and Controls

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03929627
Enrollment
80
Registered
2019-04-29
Start date
2017-04-30
Completion date
2023-10-20
Last updated
2023-10-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stress

Brief summary

It is expected that medical personnel is exposed to more work-related psychic stress compared to controls and that this burden manifests itself by an increased activity level of the resulting in higher cortisol levels and a decreased HRV. In addition, one is interested in the stress-response/coping strategies of the individuals and believe that regular physical activity might buffer the influence of stress on the HPAA-hormones and HRV.

Detailed description

Background Medical personnel is increasingly exposed to psychological stress e.g. caused by work intensification combined with time pressure, fear of job loss, lacking appreciation and/or freedom of decision, causing psychopathological or psychosomatic symptoms involving, inter alia, the cardiovascular system. The aims of the present study are the investigation of the current amount of work-related psychological stress, its perception and underlying reasons, as well as applied recovering strategies (e.g. physical activity) in Austrian health care professionals and in controls. Material and methods In total, 140 female and male participants (70 participants belong to medical staff; 70 participants belong to non-medical staff) between the ages of 25-65 years will be recruited. The individual stress perception will be evaluated using questionnaires (e.g. Trier Inventory for Chronic Stress, TICS; Brief Symptom Inventory, BSI-18, Short Work Evaluation). 24h salivary cortisol (at 5 time points) and heart rate variability (HRV) measurement will be performed to objectify the influence of stress on the physical body. The physical activity level will be tested by performing a cardiopulmonary exercise test (bicycle spiroergometry). Expected results From the present study the investigators expects insight into: first, the individual perception of work-related psychological stress among health care professionals compared to the controls; second, the association of occupational stress, HRV and laboratory stress parameters and third, the role of a good physical performance on psychological stress perception.

Interventions

OTHERCortisol awakening response

Cortisol awakening response

Sponsors

Austrian Federal Ministry of Defence
CollaboratorUNKNOWN
Medical University of Vienna
Lead SponsorOTHER

Study design

Observational model
OTHER
Time perspective
OTHER

Eligibility

Sex/Gender
ALL
Age
25 Years to 65 Years
Healthy volunteers
Yes

Inclusion criteria

* female and male participants aged 25-65 years * for Group 1: Affiliation to medical staff * for Group 2: No Affiliation to medical staff

Exclusion criteria

* Age \<25 or \>65 years * Body weight \>130 kg * Current pregnancy * Anamnestic current infectious or oncologic disease * Disability to perform a bicycle stress test * Atrial fibrillation * Pace maker/ICD implantation * Current cortison and/or dexamethasone therapy

Design outcomes

Primary

MeasureTime frameDescription
Cortisol 5Measurement of salivary cortisol before going to sleep within 24 hour testing periodMeasurement of salivary cortisol before going to sleep
Cortisol 2Measurement of salivary cortisol 30 minutes after awakening within 24 hour testing periodMeasurement of salivary cortisol 30 minutes after awakening
Cortisol 3Measurement of salivary cortisol at 10 am within 24 hour testing periodMeasurement of salivary cortisol at 10 am
Cortisol 4Measurement of salivary cortisol at 4 pm within 24 hour testing periodMeasurement of salivary cortisol at 4 pm
Cortisol 1Measurement of salivary cortisol right after awakening within 24 hour testing periodMeasurement of salivary cortisol right after awakening

Secondary

MeasureTime frameDescription
Score of the Work ability Indexonce at inclusionComparison of the score of the Work ability Index

Other

MeasureTime frameDescription
Heart rate variabilityonce at inclusion over 24 hours, measurement of the parameters every 10 minutesMeasurement of low frequencies (LF) and high frequencies (HF) by heart rate variability measurement for 24h. The measurement runs for 24h, a median value of the 24h-measurement will be provided.
Score of the Effort-Reward Imbalance Questionnaire (ERI)once at inclusionComparison of the score of the Effort-Reward Imbalance Questionnaire (ERI) by Siegrist

Countries

Austria

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026