Functional Imaging in the Acute Phase of Transient Ischemic Attacks

Contribution of Functional Imaging to the Diagnostic and Assesment of the Acute Phase of Transient Ischemic Attacks : a Preliminary Study

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03928977

Acronym

IMAGE AIT

Enrollment

Registered

2019-04-26

Start date

2019-10-15

Completion date

2021-02-28

Last updated

2019-11-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Transient Ischemic Attack

Keywords

Transient Ischemic Attack, Stroke, functional Magnetic Resonance Imaging

Brief summary

The aim of the study is to find a radiological biomarker of Transient Ischemic Attacks (TIA) thanks to functional Magnetic Resonance Imaging (fMRI) done within the 24 hour after symptoms onset.

Interventions

DIAGNOSTIC_TESTFunctional Magnetic Resonance Imaging

fMRI sequences done with motor paradigm (right and left arm), followed by resting state acquisition

Study design

Allocation

NON_RANDOMIZED

Intervention model

PARALLEL

Primary purpose

DIAGNOSTIC

Masking

SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patient admitted in for a transient neurologic deficit and suspicion of TIA of carotid circulation * Prescription for conventionnal MRI

Exclusion criteria

* Contraindication to MRI * Previous neurological disease (with lesions) * Severe psychiatric disease

Design outcomes

Primary

Measure	Time frame	Description
Blood-Oxygen-Level Dependent signal	24 hours after symptoms onset	BOLD effect differences in motor cortex from pathological side versus healthy side measured by fMRI within the 24 hours after symptom onset, during a motor paradigm

Secondary

Measure	Time frame	Description
Resting state	24 hours after symptoms onset	Bold effect differences in resting state networks from pathological side versus healthy side measured by fMRI within the 24 hours after symptom onset, during a motor paradigm

Countries

France

Contacts

Primary ContactLouise BONNET, MD

l1bonnet@chu-besancon.fr033381668984

Backup ContactGuillaume CHARBONNIER, MD

g1charbonnier@chu-besancon.fr

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026