Mild Cognitive Impairment
Conditions
Keywords
Cognitive training, Cognitive intervention, Cognitive rehabilitation
Brief summary
The purpose of this study is to examine therapeutic efficacy of cognitive Training based on location information and activity in people with mild cognitive impairment
Detailed description
* A single arm, open-label study. * Cognitive Training based on location information and activity is consists of both cognitive training and exercise(walking) using objects in the participant's home. The researchers visit the participant's home and find objects that were mainly used in the real life and easy to access (table, computer, television, etc.) and attach the recognition Bluetooth Low Energy(BLE) Tag (sticker integrated). The stickers printed on the tags consist of word categories (eg animals) belonging to a particular category, so as to assist strategic recall in the stepped recall task. The participants follow the instruction from the tablet-based program to perform the task. During performing the cognitive training program, the participants are guided to walk between the tagged objects in their home. * The participants are aged over 60 years old and diagnosed with mild cognitive impairment.
Interventions
BEHAVIORALtablet based Cognitive Training based on location information
Participants perform Tablet based Cognitive training using interactive voice services and tags three times (minimum 30 minutes per time) a week for 6 weeks
Sponsors
Institute of Information & Communications Technology Planning & Evaluation, Korea
Seoul National University Bundang Hospital
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
60 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Aged above 60 * Confirmed literacy o Diagnosed with mild cognitive impairment by International Working Group on Mild Cognitive Impairment and Clinical Dementia Rating(CDR) of 0 or 0.5.
Exclusion criteria
* Evidence of delirium, confusion * Any neurological conditions causing cognitive decline such as Parkinson's disease, brain hemorrhage, brain tumor, normal pressure hydrocephalus * Evidence of severe cerebrovascular pathology * Presence of depressive symptoms that could influence cognitive function * Presence of medical comorbidities that could result in any difficulties in study participation
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in CERAD-TS1 score | baseline and 6 weeks | Total Score of the Consortium to Establish a Registry for Alzheimer's Disease (CERAD) Neuropsychological Assessment Battery (CERAD-TS1) . CERAD-TS1 is generated by simply summing the scores of six tests including the 1) Verbal fluency (range 0-24), 2) Boston naming test (0-15), 3) Word List Memory (0-30), 4) Word List Recall (0-10), 5) Word list recognition (0-10), 6) Constructional Praxis (0-11). The range of CERAD-TS1 score is 0 to 100 points), and the higher score represents the better cognitive function. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change in MMSE score | baseline and 6 weeks | Mini-Mental State Examination (MMSE), ranged 0-30, the higher score represents the better cognitive function |
| Change in SMCQ score | baseline and 6 weeks | Subjective Memory Complaint Questionnaire (SMCQ), ranged 0-14, the higher score represents the more difficulties in memory function for everyday life |
| Change in GDS score | baseline and 6 weeks | Geriatric depression scale (GDS), ranged 0-30, the higher score represents the more severe depressive symptoms |
Countries
South Korea
Outcome results
None listed