Bio-Impedance Measurements, Edema Leg, Nocturia, Venous Insufficiency of Leg
Conditions
Brief summary
Nocturia, or waking during the night to pass urine, is a multifactorial disease. An important cause of nocturia are peripheral edema due to accumulation of fluid in the lower limbs. Venous insufficiency is an important cause of peripheral edema. The investigators hypothesize that, as a result of the lying position during the night, the accumulated fluid in the lower limbs returns to the systemical circulation leading and is excreted during nighttime. This will lead to a higher voiding frequency during the night. With this trail the investigators wanst to prove the difference in leg edema between healthy volunteers and volunteers with venous insufficiency (Type 1 or 2).
Interventions
BEHAVIORALTilt Test
Volunteers need to lay down for 15 minutes and afterwards stand up for 15 minutes
DEVICEInbody S10
Bio-electrical impedance measurement every 5 minutes
DEVICETape measurements
Every 5 minutes, circumference of every leg is measured using a tape measure
DEVICESOMNOtouchTMNIBP, Vivisol, Belgium
Continous measurement of blood pressure, heart rate and saturation
Sponsors
University Hospital, Ghent
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
25 Years to 60 Years
Healthy volunteers
Yes
Inclusion criteria
* Age between 25 years and 60 years * For the volunteers with venous insuffiency: clearly visual venous insufficiency (CEAP 1 and 2) * BMI between 24 and 30
Exclusion criteria
* Volunteers using medication (exception for contraception) * Volunteers having comorbidities * Pregnant women * Women who menstruate on the test date * Volunteers with an implanted elektronical device (IPG, Pacemaker)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Leg swelling measured in cm | 25 minutes | Difference in lower limb swelling between healthy volunteers and volunteers with venous insufficiency |
Countries
Belgium
Outcome results
None listed