Overweight and Obesity
Conditions
Brief summary
This investigations examined the effect that posture has on metabolic and cardiovascular measurements. Further, it will explore the potential for body weight status or physical activity to influence these relationships. All subjects will complete a seated condition and a standing condition in a counterbalanced manner.
Detailed description
The purpose of the present study was to evaluate both metabolic and cardiovascular responses to acute bouts of computer work while sitting and standing. Cardiovascular measurements were made using continuous non-invasive blood pressure monitoring and metabolic measurements were made using indirect calorimetry. Subjects will be grouped and analyzed based upon the weight status of the subject. All subjects will complete a seated condition and a standing condition in a counterbalanced manner. Investigators hypothesize that metabolic and cardiovascular responses will be elevated in the standing condition compared to sitting.
Interventions
BEHAVIORALsit/stand
Subjects will be asked to both sit and stand during a single trial.
Sponsors
Montclair State University
Study design
Observational model
COHORT
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to 50 Years
Healthy volunteers
No
Inclusion criteria
* healthy adult
Exclusion criteria
* Have a history of cancer, cardiac issues, hypertension, pulmonary disease, stroke, neurological or muscular dystrophy, uncontrolled diabetes, or any life threatening chronic conditions. * Are currently being treated for infectious mononucleosis, hepatitis, pneumonia, or other infectious diseases. * Are unable or unwilling to stand in one position continuously for 15-20 minutes at a time. * Use nicotine products, or non-contraceptive hormonal therapy (birth control is okay). * Are pregnant or trying to become pregnant. * Are not between 18 and 50 years of age.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Heart Rate | Approximately 15 minutes in each condition (sitting and standing) | Using human non-invasive blood pressure continuous monitoring placed on the middle finger of the non-dominant hand will be used to measure heart rate based upon beat-by-beat finger pressure. |
| Systolic Blood Pressure (SBP) | Approximately 15 minutes in each condition (sitting and standing) | Using human non-invasive blood pressure continuous monitoring placed on the middle finger of the non-dominant hand will be used to measure SBP based upon beat-by-beat finger pressure. |
| Diastolic Blood Pressure (DBP) | Approximately 15 minutes in each condition (sitting and standing) | Using human non-invasive blood pressure continuous monitoring placed on the middle finger of the non-dominant hand will be used to measure DBP based upon beat-by-beat finger pressure. |
| Oxygen Consumption | Approximately 15 minutes in each condition (sitting and standing) | Oxygen consumption will be measured using indirect calorimetry. |
| Carbon Dioxide Production | Approximately 15 minutes in each condition (sitting and standing) | Carbon Dioxide will be measured using indirect calorimetry. |
| Ventilation | Approximately 15 minutes in each condition (sitting and standing) | Ventilation will be measured using indirect calorimetry. |
| Respiratory Exchange Ration (RER) | Approximately 15 minutes in each condition (sitting and standing) | RER will be calculated using oxygen and carbon dioxide value measure from indirect calorimetry. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Height | 1 minute | Standard stadiometer will be used to measure height in meters. |
| Muscle Oxygen Saturation | Approximately 15 minutes in each condition (sitting and standing) | Using Near-inferred spectroscopy muscle oxygen consumption will be monitored. |
| Weight | 1 minute | Standard scale will be used to measure weight in kilograms. |
| Body Mass Index (BMI) | 1 minute | Height in meters and weight in kilograms will be used to calculate BMI using the formula BMI = kg/m\^2. |
| Body Composition | Approximately 15 minutes | Body composition will be measured using air displacement plethysmography. |
| Total Peripheral Resistance (TPR) | Approximately 15 minutes in each condition (sitting and standing) | Using human non-invasive blood pressure continuous monitoring placed on the middle finger of the non-dominant hand will be uses to estimate TPR based upon beat-by-beat finger pressure. |
| Stroke Volume | Approximately 15 minutes in each condition (sitting and standing) | Using human non-invasive blood pressure continuous monitoring placed on the middle finger of the non-dominant hand will be used to estimate TPR based upon beat-by-beat finger pressure. |
| Cardiac Output (Q) | Approximately 15 minutes in each condition (sitting and standing) | Using human non-invasive blood pressure continuous monitoring placed on the middle finger of the non-dominant hand will be used to estimate Q based upon beat-by-beat finger pressure. |
Countries
United States
Outcome results
None listed