Age Related Macular Degeneration, Epiretinal Membrane, Macular Holes
Conditions
Brief summary
Surgical outcome of patients with macular drusen and co-existing abnormalities of the vitreoretinal interface, who routinely undergo pars plana vitrectomy with membrane peeling, is evaluated. Best corrected visual acuity as well as optical coherence tomography data are compared at baseline and last follow up. The rate of development of choroidal neovascularization postoperatively is noted.
Interventions
PROCEDUREpars plana vitrectomy with membrane peeling
23-gauge pars plana vitrectomy with peeling of the epiretinal and internal limiting membrane as well as air- or gastamponade
Sponsors
Klinikum Chemnitz gGmbH
Study design
Observational model
CASE_ONLY
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
1. participants diagnosed with ERM or FTMH and co-existing macular drusen; 2. undergone pars plana vitrectomy with ILM and epiretinale membrane peeling; 3. SD-OCT at the initial visit and at last follow up visit with image quality score \>30; 4. no evidence of CNV on initial fluorescein angiography (FA).
Exclusion criteria
1. history of other macular disease, severe non-proliferative or proliferative diabetic retinopathy, other retinal vascular diseases, glaucoma, myopic retinopathy, or other diseases interfering with OCT images in any one of the eyes; 2. active CNV or history of CNV
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| number of patients with CNV | last visit, in common 6 months postoperatively | number of patients with CNV (choroidal neovascularization) development |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| BCVA | last visit, in common 6 months postoperatively | best corrected visual acuity |
| incidence of central retinal atrophy | last visit, in common 6 months postoperatively | development of central retinal atrophy on OCT |
Countries
Germany
Outcome results
None listed