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Effect of Different Infusion Volume on Perioperative Bladder and Blood Volume in Patients Undergoing Daytime Surgery.

Effect of Different Infusion Volume on Perioperative Bladder and Blood Volume in Patients Undergoing Daytime Surgery.

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03924804
Enrollment
90
Registered
2019-04-23
Start date
2019-06-19
Completion date
2022-05-12
Last updated
2022-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cholecystolithiasis and Thyroid Nodule

Brief summary

The objective of the trial was to explore the effect of different infusion volume on perioperative bladder and blood volume in patients undergoing daytime surgery assisted by bladder and vascular ultrasound and transthoracic echocardiography.

Detailed description

The objective of the trial was to evaluate the effects of different infusion volume of Ringer's solution acetate (2 ml/kg,8ml/kg, 16ml/kg) on bladder volume, hemodynamics,transthoracic echocardiography and vascular ultrasound including the inferior vena cava(IVC) and the right subclavian vein(SCV) diameter and the IVC and SCV collapsibility index in patients undergoing daytime surgery through a randomized controlled clinical study, so as to provide better guidance for clinical transfusion avoiding bladder catheterization . The patients in this trial were visited before induction and discharge from the postanaesthesia .We also collected the first time and times of micturition and whether the patients have the dysuria.

Interventions

DRUGRinger's solution acetate

Intravenous infusion of 2 ml/kg Ringer's solution acetate within 1 hour after induction.

Sponsors

China Medical University, China
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)

Intervention model description

Doppler Ultrasonography Assessed Bladder and Blood Volume

Eligibility

Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No

Inclusion criteria

* 1\. ethnic Chinese; * 2\. age, 18 to 65 years old; * 3\. American Society of Anaesthesiologists (ASA) physical status I or II; * 4\. Daytime patients scheduled for general anesthesia

Exclusion criteria

* Patients unwilling to cooperate with the experiment * Body mass index exceeding 30 kg/m2; * Patients with a history of heart ,liver and Renal failure ,hypertension,diabetes mellitus or arteriosclerosis; and any allergy to drugs used in the study. * Patients with the urinary diseases, such as kidney, ureteral calculi and tumors, prostatic hypertrophy.

Design outcomes

Primary

MeasureTime frameDescription
1. The change of bladder volumebaseline and 10 minutes before leaving the post-anesthesia care unitebladder and blood volume in patients undergoing daytime surgery assisted by bladder and vascular ultrasound

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026