Acne Vulgaris
Conditions
Brief summary
This study seeks to examine if there is any relationship between spironolactone use prescribed for acne vulgaris and depression, anxiety, and/or sexual function.
Interventions
OTHEROnline survey
Online survey completion through Northwestern's REDCap
Sponsors
Northwestern University
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 65 Years
Inclusion criteria
Female subjects between 18 and 65 years of age currently taking spironolactone for a diagnosis of acne vulgaris OR Female subjects between 18 and 65 years of age currently taking oral antibiotics for a diagnosis of acne vulgaris AND Subjects able to complete an online survey in English
Exclusion criteria
Subjects less than 18 years of age or older than 65 years of age Subjects that have ever been diagnosed with any mood disorder by a clinician prior to starting spironolactone (history of mood disorder or current mood disorder) Subjects taking hormonal contraception (including but not limited to oral contraceptive pills) for a duration of less than 6 months Subjects that have ever been diagnosed with any type of sexual dysfunction prior to starting spironolactone Subjects not able to complete an online survey in English Subjects taking oral isotretinoin for a diagnosis of acne Subjects that are currently pregnant
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Percent correlation between spironolactone use for acne vulgaris and increased prevalence of depression. | one week | Score for depression from subject reported Dermatology Life Quality Index (DLQI) survey |
| Percent correlation between spironolactone use for acne vulgaris and increased prevalence of anxiety. | two weeks | Score for depression from subject reported Generalized Anxiety Disorder (GAD-7) survey |
| Percent correlation between spironolactone use for acne vulgaris and increased prevalence of sexual dysfunction. | four weeks | Score for depression from subject reported Female Sexual Function Index (FSFI) survey. |
Countries
United States
Outcome results
None listed