Metabolic Problems
Conditions
Brief summary
The investigators conduct a randomized, double-blind, placebo-controlled study to investigate the effects of oral ingestion of drinking water using a tumbler that emits far infrared rays at room temperature on metabolic profile in adults for 8 weeks.
Detailed description
The investigators conduct a randomized, double-blind, placebo-controlled study to investigate the effects of oral ingestion of drinking water using a tumbler that emits far infrared rays at room temperature on metabolic profile in adults for 8 weeks; the safety of the compound are also evaluate. The Investigators examine lipid profile, glucose, liver and renal function at baseline, as well as after 4, 8 weeks of intervention. Thirty adults were administered either 1.8 L of drinking water using a tumbler that emits far infrared rays at room temperature or drinking water using a sham-tumbler each day for 12 weeks.
Interventions
DIETARY_SUPPLEMENTinfrared water group
This group takes 1,8 L of drinking water using a tumbler that emits far infrared rays at room temperature.
DIETARY_SUPPLEMENTsham group
This group takes 1,8 L of drinking water using a tumbler at room temperature.
Sponsors
Pusan National University Yangsan Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
19 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* 19 years and older
Exclusion criteria
* aspartate aminotransferase (AST) or alanine aminotransferase (ALT) more than twice the highest reference value * serum creatinine ≥ 1.5 mg/dL) * uncontrolled diabetes mellitus (a fasting glucose of \>160 mg/dL) * uncontrolled hypertension (BP \> 160/100 mmHg) * severe gastrointestinal symptoms * alcohol abuser * pregnant or lactating women * allergic to the ingredient involved * cardiocebrovascular diseases or any cancer during the six months prior to study * smoker
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Low density lipoprotein cholesterol (LDL-C) | Change from baseline level of LDL-C at 8 weeks | Change of LDL-C during 8 weeks |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| alanine transaminase (ALT) | Change from baseline level of ALT at 8 weeks | Change of ALT during 8 weeks |
| homeostasis model assessment of insulin resistance (HOMA-IR) | Change from baseline level of HOMA-IR at 8 weeks | Change of HOMA-IR during 8 weeks |
| free fatty acid | Change from baseline level at 8 weeks | Change of free fatty acid during 8 weeks |
| aspartate transaminase (AST) | Change from baseline level of AST at 8 weeks | Change of AST during 8 weeks |
| creatinine | Change from baseline level of creatinine at 8 weeks | Change of creatinine during 8 weeks |
| body weight | Change from baseline level at 8 weeks | Change of body weight during 8 weeks |
Countries
South Korea
Outcome results
None listed