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Comparison of The Effects of Concentric And Eccentric Isokinetic Exercises in Patients With Knee Osteoarthritis

Comparison of The Effects of Concentric and Eccentric Isokinetic Exercises on Proprioception and Muscle Architecture in Patients With Knee Osteoarthritis

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03920020
Enrollment
43
Registered
2019-04-18
Start date
2019-01-28
Completion date
2021-12-31
Last updated
2023-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee Osteoarthritis

Keywords

Concentric, Eccentric, Muscle Architecture, Proprioception

Brief summary

This study aims to compare the effects of concentric and eccentric isokinetic exercises on proprioception and muscle architecture in 42 patients with knee osteoarthritis enrolled the study.

Detailed description

This study aims to compare the effects of concentric and eccentric isokinetic exercises on proprioception and muscle architecture in patients with knee osteoarthritis. 42 patients will be included in this study. Patients will be divided into three groups; concentric exercise group (n:14), eccentric exercise group (n:14) and control group (n:14). A conventional physiotherapy program and a standard therapeutic exercise program will be applied to all subjects. In addition to these exercise and physiotherapy programme, concentric and eccentric exercise groups will perform the exercises related to their groups. All three groups will participate in this program for a total of 18 sessions 3 times a week for 6 weeks. All groups will be subject to re-evaluation after 6 weeks.

Interventions

OTHERthe concentric isokinetic exercise group

concentric isokinetic exercises

OTHERthe eccentric isokinetic exercise group

eccentric isokinetic exercises

OTHERthe control group

conventional physiotherapy and standard therapeutic exercises predetermined by us

Sponsors

Hacettepe University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)

Eligibility

Sex/Gender
ALL
Age
45 Years to 65 Years
Healthy volunteers
No

Inclusion criteria

* Diagnosis of primary knee osteoarthritis according to American College of Radiology * Being radiographically K-L grade 2-3 * Presence of symptoms for at least 3 months * Patients who have been planned a conventional physiotherapy programme because of knee osteoarthritis * Presence of functional capacity for outpatient physical therapy

Exclusion criteria

* Patients with seconder knee osteoarthritis * History of lower extremity or spine surgery * History of intraarticular injection in last 1 month * Patients with neurological disease that will affect muscle strength, balance and coordination

Design outcomes

Primary

MeasureTime frameDescription
Joint position sense6 weeksJoint position sense will be evaluated with isokinetic dynamometer at predetermined angles.
Ultrasonographic assessment of quadriceps and hamstring muscles6 weeksUltrasonographic evaluation is an outcome measure to evaluate muscle structure. In our study ultrasonographic evaluation will be performed to determine the muscle structure (muscle thickness(mm), fascicle length(mm), pennation angle(degree)) of quadriceps and hamstring muscles. Muscle thickness will be defined as the distance between the deeper and upper aponeurosis. The pennation angle will be calculated as the angle of insertion of muscle fascicles into the deep aponeurosis. Fascicle length will be defined as the length of the fascicular path between the superficial and deep aponeurosis.

Secondary

MeasureTime frameDescription
Muscle strength assessment6 weeksisokinetic dynamometer test will be used.
Shortness of muscles assessment6 weeksuniversal goniometer will be used for assessment
Pain assessment: VAS (Visual analog scale)6 weeksVAS is used to measure the psycometric pain severity in some conditions and activities. A VAS is usually a 100 mm long horizontal line. The scale is most commonly anchored by no pain (line's left, score-0), pain as bad as it could be (line's right, score-100). the score is determined by measuring the distance between the no pain anchor and the patient's mark.
Balance assessment6 weeksSingle leg standing test with eyes open and closed will be used. Timing is recorded.
WOMAC (Western Ontario & McMaster Universities Osteoarthritis Index)6 weeksWOMAC Osteoarthritis Index (score range 0-100) include 3 subscales and will be used to evaluate knee pain(score range 0-20), stiffness (score range 0-8), and functional limitation (score range -68). Womac is comprised of 24 items ( pain-5 items, stiffness-2 items, physical function-17 items). All items are scored on a scale of 0-4. Lower scores indicate lower disability.
Sit to stand test6 weeksPatients stand up from and sit down on a chair as quickly as possible 5 times. Patients folded their arms across their chests. Timing is recorded.
Timed 10 meter walk test6 weeksThis test is used to assess walking speed. Timing is recorded.
Short Form 12 (SF-12) health survey6 weeksSF-12 is an 12- item questionnare for assessing self-reported health related quality of life. It covers eight domains of health outcomes, including physical functioning, role physical, bodily pain, general health, vitality, social functioning,role-emotional, mental health. Sf-12 physical and mental component summary scales are scored. Lower SF-12 score indicated poorer physical and mental health.
The timed up and go test6 weeksTUG test is used to measure functional mobility. It gives an idea about patients walking ability, fall risk and balance. The patient is asked to get up, walk 3 meters and sit down again.Timing begins when the patient rise from the chair and stops when the patient sit down.
Range of motion6 weeksUniversal goniometer will be used for assessment of range of motion of the knee

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026