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Identification of Risk Factors for Atrial Fibrillation After Ablation of an Atrial Flutter by Radiofrequency of the Cavotricuspid Isthmus.

Retrospective Study to Identify Risk Factors for Atrial Fibrillation After Ablation of Atrial Flutter by Radiofrequency of the Cavotricuspid Isthmus.

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03919097
Enrollment
50
Registered
2019-04-18
Start date
2019-01-08
Completion date
2019-11-20
Last updated
2022-07-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Flutter

Brief summary

Atrial flutter is a common condition that is effectively treated by ablation using radiofrequency. Due to its feasibility, effectiveness and low procedural risk, radiofrequency ablation is a first-line treatment of atrial flutter. Several studies have been published concerning the factors associated with the occurrence of atrial fibrillation during or after flutter ablation, in patients with and without clinical history of atrial fibrillation. 26 to 46% of patients are likely to develop it, according to ECG or Holter diagnoses. The figure rises to more than 50% with a diagnosis with an implantable loop recorder. In patients without a prior history of atrial fibrillation before ablation, anticoagulants are routinely administered 4-6 weeks after flutter removal by most cardiologists. Although there are no specific guidelines for anticoagulation after flutter ablation, it is currently recommended to treat the patient as for atrial fibrillation. It is therefore crucial to identify in advance patients at high risk of atrial fibrillation after flutter ablation, in order to assess the appropriateness of maintaining oral anticoagulant therapy. The objectives of this study are: * to evaluate the frequency and identify the factors predicting the occurrence of atrial fibrillation after flutter ablation * to determine the risk of a stroke occurring in patients with atrial fibrillation after flutter ablation. The database consists in patients of the CHU Brugmann Hospital treated between 1996 and 2018.

Interventions

Data extraction from the patient's Medical Files

Sponsors

José Castro
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

Patients treated at the CHU Brugmann Hospital for flutter ablation by radiofrequency between 1996 and 2018.

Exclusion criteria

None

Design outcomes

Primary

MeasureTime frameDescription
Age at ablationOne dayAge of the patient at the date of the flutter ablation
GenderOne dayGender of the patient at the date of the flutter ablation
Antecedents of ischemic cardiomyopathyOne dayAntecedents of ischemic cardiomyopathy (yes/no) at the date of flutter ablation
Antecedents of cardiomyopathyOne dayAntecedents of cardiomyopathy (yes/no) at the date of flutter ablation
Antecedents of dilated cardiomyopathyOne dayAntecedents of dilated cardiomyopathy (yes/no) at the date of flutter ablation
DiabetesOne dayDiabetes diagnosis (yes/no) at the date of flutter ablation
Chronic pulmonal diseaseOne dayChronic pulmonal disease diagnosed at the date of flutter ablation
Cardiac surgery antecedentsOne dayPresence of cardiac surgery antecedents at the date of flutter ablation
Atrial fibrillation antecedentsOne dayAntecedents of Atrial fibrillation at the date of flutter ablation
Beta-blockers post-ablationOne dayPrescription of Beta-Blockers after the flutter ablation (yes/no)
Amiodarone post-ablationOne yearPrescription of amiodarone after the flutter ablation (yes/no)
Class I antiarrhythmic drugs post-ablationOne yearPrescription of Class I antiarrhythmic drugs post-ablation
Arterial hypertensionOne dayPresence of arterial hypertension on the day of flutter ablation
Antecedents of strokeOne dayAntecedents of stroke
Stroke after flutter ablationOne yearOccurence of stroke after the flutter ablation
Antecedents of peripheric thromboembolic eventsOne dayAntecedents of thromboembolic events on the day of flutter ablation
Peripheric thromboembolic events after flutter ablationOne yearThromboembolic events after flutter ablation
Atrial Fibrillation apparition delayUp to one yearDelay of apparition of atrial fibrillation after flutter removal
Left ventricular ejection fraction of the heartOne dayLeft ventricular ejection fraction of the heart at the day of flutter removal (echographic data)
Left atrium size of the heartOne dayLeft atrium size of the heart at the day of flutter removal (echographic data)
Pulmonary arterial pressureOne dayPulmonary arterial pressure at the day of flutter removal (echographic data)

Countries

Belgium

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026