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Effectiveness of Khat on Eyelid Wound Healing After Oculoplastic Surgery - a Prospective Study.

Effectiveness of Khat on Eyelid Wound Healing After Oculoplastic Surgery - a Prospective Study.

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03917641
Enrollment
10
Registered
2019-04-17
Start date
2019-07-01
Completion date
2021-07-01
Last updated
2019-04-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Edema, Eye Bruise, Hematoma, Surgery, Surgical Wound

Keywords

Oculoplastic Surgery, Khat leaves, Post operative care, Edema, Hematoma

Brief summary

The post operative routine after Oculoplastic Surgery includes usage of cold compressions for symptomatic relief and decreasing of the edema and local hematomas in the first few days after the surgery. Khat (Catha edulis) is a plant that is used mainly for chewing and has a known stimulating effect, some patients report major improvement after including these leaves in the compressions they use after surgery. Khat contains the chemical ingredients Cathine and Cathinone, which are amphetamine-like alkaloids and probably the main contributors for its active effects. Our main goal is to use compressions that include the Khat leaves and check their effect on reducing the edema and hematomas after oculoplastic surgery.

Interventions

BIOLOGICALKhat leaves

One of the two compressions (one per each eye) the patient will use will contain the Khat leaves.

Sponsors

Sheba Medical Center
Lead SponsorOTHER_GOV

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE

Intervention model description

Each participant is his own control

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* Patients who underwent blepharoplasty and/or ptosis repair

Exclusion criteria

* Patients who were operated on one eye only * Patients who underwent a different surgery in each eye

Design outcomes

Primary

MeasureTime frameDescription
Edema7 days post opImprovement in edema in the Khat compression in comparison to standard compression by clinical evaluation.
Hematoma7 days post opImprovement in hematomas in the Khat compression in comparison to standard by compression by clinical evaluation.

Countries

Israel

Contacts

Primary ContactGuy J Ben Simon, MD
guybensimon@gmail.com97235302874

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026