Von Willebrand Disease, Type 1
Conditions
Keywords
von willebrand, egyptian, questionnaire
Brief summary
Applying the ISTH-BAT questionnaire on Egyptian patients with type I VWD aiming to correlate the BS with the laboratory findings
Detailed description
The clinical phenotype of the disease is variable and tends to be mild in type 1 vWD, whereas it shows serious bleeding manifestations in types 2 and 3. Overall, the symptoms reported in vWD include easy bruising, epistaxis, gastrointestinal bleeding, excessive menstrual bleeding, postpartum haemorrhage, and excessive bleeding after surgical operation and minor wounds.However, A distinctive bleeding history is a prerequisite for the diagnosis of any bleeding disorder and should guide further laboratory investigations In an attempt to standardize the diagnostic criteria of VWD, a bleeding questionnaire and a bleeding score were developed The combination of a standardized bleeding questionnaire and a well-defined interpretation grid (for the computation of the final (BS) has been referred to as a Bleeding Assessment Tool (BAT).
Interventions
blood sample
Sponsors
Study design
Eligibility
Inclusion criteria
* type 1 vWD patients * healthy subjects with no known problem with bleeding or bruising were also recruited
Exclusion criteria
\-
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| the International Society on Thrombosis and Hemostasis-Bleeding Assessment Tool (ISTH-BAT) | one year | Questionnaire minimum score ranges from 0 to 10 whereas maximum score ranges from 20 to 30 |